The effect of the phytocomplex Renotineх® on postoperative period after external shock wave lithotripsy in patients with urolithiasis
- Authors: Neymark A.I.1, Neymark B.A.1, Nozdrachev N.A.1, Gatkin M.Y.2, Fursa Y.S.1
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Affiliations:
- Altai State Medical University of the Ministry of Healthcare of the Russian Federation
- City Clinical Hospital No. 11
- Issue: Vol 11, No 1 (2021)
- Pages: 49-54
- Section: Original articles
- URL: https://bakhtiniada.ru/uroved/article/view/34756
- DOI: https://doi.org/10.17816/uroved34756
- ID: 34756
Cite item
Abstract
INTRODUCTION: Phytopreparations are one of the leading medicines used as preoperative preparation and postoperative management in patients with urolithiasis.
THE AIM of the study was to evaluate the nephroprotective effect of Renotinex® in patients with urolithiasis after extracorporeal shock wave lithotripsy (ESWL).
MATERIALS AND METHODS: The study included 86 patients (43 in the main and the comparison group) with urolithiasis with localization of the stone in the renal pelvis without disturbing the outflow of urine. All patients underwent extracorporeal shock wave lithotripsy (ESWL). After ESWL patients in both groups received spasmodic, anti-inflammatory, antibacterial therapy. Patients of the main group additionally received Renotinex® 2 capsules 3 times a day for 14 days before and 14 days after surgery.
RESULTS: During the observation a more effective discharge of calculus fragments was noted in patients of the main group while taking the phytocomplex Renotinex®, as well as less pronounced damage and faster recovery of the renal parenchyma after ESWL according to the level of enzimuria.
CONCLUSION: The results of the study indicate the feasibility of prescribing the phytocomplex Renotinex® for nephroprotective and lithokinetic therapy in patients after ESWL.
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##article.viewOnOriginalSite##About the authors
Aleksandr I. Neymark
Altai State Medical University of the Ministry of Healthcare of the Russian Federation
Email: neimark.a@mail.ru
ORCID iD: 0000-0002-5741-6408
SPIN-code: 4528-7765
Scopus Author ID: 7102411541
https://asmu.ru/ob-universitete/fakultety/lechebnyy-fakultet/spetsializirovannoy-khirurgii-po-urologii-travmatologii-i-oftalmologii/#
Doc. Sci. (Med.), Professor, Head of the Department of Urology and Andrology with a Course of Additional Professional Education
Russian Federation, 656038, Altai region, Barnaul, Lenina prospekt, 40Boris A. Neymark
Altai State Medical University of the Ministry of Healthcare of the Russian Federation
Email: neimark.b@mail.ru
ORCID iD: 0000-0001-8009-3777
SPIN-code: 7886-8442
https://asmu.ru/ob-universitete/fakultety/lechebnyy-fakultet/spetsializirovannoy-khirurgii-po-urologii-travmatologii-i-oftalmologii/#
Doc. Sci. (Med.), Professor of the Department of Urology and Andrology with a Course of Additional Professional Education
Russian Federation, 656038, Altai region, Barnaul, Lenina prospekt, 40Nikolay A. Nozdrachev
Altai State Medical University of the Ministry of Healthcare of the Russian Federation
Author for correspondence.
Email: nozdrachevuro@mail.ru
ORCID iD: 0000-0001-9203-3499
SPIN-code: 4800-8255
Cand. Sci. (Med.), associate professor of Department of Urology and Andrology with a Course of Additional Professional Education
Russian Federation, 656038, Altai region, Barnaul, Lenina prospekt, 40Michail Y. Gatkin
City Clinical Hospital No. 11
Email: gatkin@mail.ru
Cand. Sci. (Med), Urologist of the Urological Department
Russian Federation, 656050, Altai region, Malahova street, 51Yulia S. Fursa
Altai State Medical University of the Ministry of Healthcare of the Russian Federation
Email: baryshnikova2010@yandex.ru
Clinical resident of the Department of Urology and Andrology with a Course of Additional Professional Education
Russian Federation, 656038, Altai region, Barnaul, Lenina prospekt, 40References
- Apolikhin OI, Sivkov AV, Moskaleva NG, et al. Analysis of the uro-nephrological morbidity and mortality in the Russian Federation during the 10-year period (2002–2012) according to the official statistics. Experimental and Clinical Urology. 2014;(2):4–13. (In Russ.)
- Alyaev YuG, Glybochko PV, Pushkar DYu. Urology. Russian clinical recommendations. Moscow: Medforum; 2017;78–126. (In Russ.)
- Rudenko VI, Semenyakin IV, Malkhasyan VA, Gadzhiev NK. Urolythiasis. Urologiya. 2017;(2 S2):30–63. (In Russ.)
- Ensebaev EZ, Bajgaskinov ZK. Results of extracorporeal shock wave lithotripsy in patients with high density kidney calculi. Urology reports (St. Petersburg). 2020;10(3):235–241. (In Russ.) doi: 10.17816/uroved33783
- Khasigov AV, Khazhokov MA, Ilyash AV, et al. Effectiveness and safety of extracorporeal shockwave lithotripsy for uncomplicated pelvic concrements. Urology Herald. 2017;5(3):39–48. (In Russ.) doi: 10.21886/2308-6424-2017-5-3-39-48
- Sitdykova ME, Kuzmina FM. Efficacy of a plant complex prolit after extracorporeal lithotripsy in patients with urolithiasis. Urologiia. 2006;(3):57–60. (In Russ.)
- Popkov VM, Osnovin OV, Fomkina OA. Results of using of terpens-based medication renotinex in patients with urolithiasis after extracorporeal shockwave lithotripsy. Urology reports (St. Petersburg). 2020;10(1):39–42. (In Russ.) doi: 10.17816/uroved10139–42
- Sharaev PN, Gabdrahmanova NK, Strelkova TN, Sahabutdinova EP. A method of determining the activity of N-acetyl-β-D-hexosaminidase in urea. Russian Clinical Laboratory Diagnostics. 2004;(5):40–42 (In Russ.)
- Glanc S. Primer of Biostatistics. M.: Praktika; 1998. P. 459. (In Russ.)
- Kehrer G, Blech M, Kallerhoff M, Bretschneider HJ. Urinary LDH-release for evaluation of postischemic renal function. Klin Wochenschr. 1989;67(9):477–485. doi: 10.1007/BF01721673.
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