Multiple recurrent condylomata acuminata of the peni

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Condylomata acuminata of the penis are a type of anogenital venereal warts characterized by exophytic growths on the skin of the external genitalia and the mucosa of the urethra. They are caused by human papillomavirus (HPV) types 6, 11, 16, 18, 31, 33, and 35, with types 6 and 11 being the most pathogenic. The virus is primarily transmitted sexually, entering the bloodstream through mucosal or skin defects during unprotected intercourse. The presented clinical case highlights the necessity of combining surgical treatment with local and systemic pharmacotherapy in a young patient with multiple recurrent condylomata acuminata of the glans and foreskin that were resistant to conservative treatment. A combination of prolonged antiviral therapy and topical application of podophyllotoxin proved insufficient, leading to widespread penile involvement. Persistent disease progression was attributed to infection with HPV type 6. The surgical intervention included circumcision, frenuloplasty, excision of residual warts on the glans, and electrocauterization of affected skin areas, followed by antiviral therapy with interferon, which resulted in complete clinical recovery. No recurrence was observed within six months.

作者简介

Aleksandr Gorbunov

Kirov Military Medical Academy

Email: vmaaaa@yandex.ru
SPIN 代码: 4863-3123
俄罗斯联邦, Saint Petersburg

Nikolai Iglovikov

Kirov Military Medical Academy

编辑信件的主要联系方式.
Email: iglovikov@yandex.ru
ORCID iD: 0009-0006-2027-9573
SPIN 代码: 5194-9604

MD, Cand. Sci. (Medicine)

俄罗斯联邦, Saint Petersburg

Vasilii Karandashov

Kirov Military Medical Academy

Email: karandashov_vk@mail.ru
ORCID iD: 0009-0001-5155-9491
SPIN 代码: 2872-9996
俄罗斯联邦, Saint Petersburg

Vladimir Protoshchak

Kirov Military Medical Academy

Email: protoshakurology@mail.ru
ORCID iD: 0000-0002-4996-2927
SPIN 代码: 6289-4250

MD, Dr. Sci. (Medicine), Professor

俄罗斯联邦, Saint Petersburg

Mikhail Paronnikov

Kirov Military Medical Academy

Email: paronnikov@mail.ru
ORCID iD: 0009-0005-1762-6100
SPIN 代码: 6147-7357

MD, Dr. Sci. (Medicine)

俄罗斯联邦, Saint Petersburg

Nikolai Kushnirenko

Kirov Military Medical Academy

Email: nikolaj.kushnirenko@yandex.ru
ORCID iD: 0009-0004-1960-4696
SPIN 代码: 3892-8959

MD, Dr. Sci. (Medicine)

俄罗斯联邦, Saint Petersburg

Nikolai Kharitonov

Kirov Military Medical Academy

Email: kharitonov@mail.ru
SPIN 代码: 9614-3001

Cand. Sci. (Medicine)

俄罗斯联邦, Saint Petersburg

Pavel Babkin

Kirov Military Medical Academy

Email: pavelbabkin@yandex.ru
SPIN 代码: 6551-4494

MD, Dr. Sci. (Medicine)

俄罗斯联邦, Saint Petersburg

参考

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2. Fig. 1. Multiple recurrent condylomata acuminata of the penis

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3. Fig. 2. Stages of surgical intervention: a, penis with an exposed glans before surgery; b, circular excision of the foreskin; c, final outcome of surgical treatment

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