Urine microbiota and bladder cancer
- Authors: Lisitsyn I.Y.1, Maistrenko D.N.1, Granov D.A.1, Rumyantseva S.Y.1, Molchanov O.E.1, Punchenko O.E.2,3
-
Affiliations:
- Granov Russian Research Center of Radiology and Surgical Technologies
- North-Western State Medical University named after I.I. Mechnikov
- Institute of Experimental Medicine
- Issue: Vol 14, No 3 (2024)
- Pages: 315-330
- Section: Reviews
- URL: https://bakhtiniada.ru/uroved/article/view/277115
- DOI: https://doi.org/10.17816/uroved633922
- ID: 277115
Cite item
Abstract
Urine analysis data obtained using modern microbiological methods and 16S rRNA gene sequencing technology indicate that the urinary system has its own microbial ecosystem. Individual microbiota members can play a key role in the development of cancer. Certain bacterial taxa have been revealed in bladder urothelial carcinoma cells that can affect carcinogenesis, treatment response, and the development of relapses through various mechanisms. The studies are conducted to use not only vaccine strains, but also probiotic strains and oncolytic bacteria for the treatment and prevention of relapses.
Keywords
Full Text
##article.viewOnOriginalSite##About the authors
Igor Yu. Lisitsyn
Granov Russian Research Center of Radiology and Surgical Technologies
Author for correspondence.
Email: urologlis@mail.ru
MD, Cand. Sci. (Medicine)
Russian Federation, Saint PetersburgDmitrii N. Maistrenko
Granov Russian Research Center of Radiology and Surgical Technologies
Email: may64@inbox.ru
ORCID iD: 0000-0001-8174-7461
SPIN-code: 7363-4840
MD, Dr. Sci. (Medicine)
Russian Federation, Saint PetersburgDmitrii A. Granov
Granov Russian Research Center of Radiology and Surgical Technologies
Email: da_granov@rrcrst.ru
ORCID iD: 0000-0002-8746-8452
SPIN-code: 5256-2744
MD, Dr. Sci. (Medicine), Professor, Academician of the Russian Academy of Sciences
Russian Federation, Saint PetersburgSvetlana Yu. Rumyantseva
Granov Russian Research Center of Radiology and Surgical Technologies
Email: si_rumiantseva@rrcrst.ru
MD, Cand. Sci. (Medicine)
Russian Federation, Saint PetersburgOleg E. Molchanov
Granov Russian Research Center of Radiology and Surgical Technologies
Email: molchanovo@mail.ru
ORCID iD: 0000-0003-3882-1720
SPIN-code: 5557-6484
MD, Dr. Sci. (Medicine)
Russian Federation, Saint PetersburgOlga E. Punchenko
North-Western State Medical University named after I.I. Mechnikov; Institute of Experimental Medicine
Email: olga.punchenko@szgmu.ru
ORCID iD: 0000-0002-1847-3231
SPIN-code: 5029-7130
MD, Cand. Sci. (Medicine)
Russian Federation, Saint Petersburg; Saint PetersburgReferences
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