Email this article Complex treatment of patients with chronic bacterial prostatitis using biologically active peptides
- Authors: Neymark A.I.1, Davydov A.V.1, Kablova I.V.1
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Affiliations:
- Altai State Medical University
- Issue: Vol 12, No 3 (2022)
- Pages: 221-228
- Section: Original articles
- URL: https://bakhtiniada.ru/uroved/article/view/109913
- DOI: https://doi.org/10.17816/uroved109913
- ID: 109913
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Abstract
BACKGROUND: Increasing the effectiveness of the treatment of chronic bacterial prostatitis is an actual problem of modern urology.
AIM: The aim of the study was to study the effectiveness of complex treatment of patients with chronic bacterial prostatitis using Prostatex.
MATERIALS AND METHODS: This study included 94 patients with chronic bacterial prostatitis aged 21 to 45 years. Patients of group I (n = 47) received standard antibiotic therapy (levofloxacin at a dose of 500 mg 2 times a day for 28 days), and patients of group II (n = 47) received standard antibiotic therapy combined with the prescription of Prostatex in the form of rectal suppositories 10 mg once a day.
RESULTS: The overall clinical efficacy of treatment in patients of group II was 2 times higher than in patients of group I. After treatment in patients of group II compared with group I a statistically significant decrease in chronic bacterial prostatitis symptoms according to the NIH-CPSI and IPSS questionnaires was recorded. Eradication of microflora in 91.4% of patients of group II was achieved, there was a significant decrease in prostate volume, an increase in the average volumetric flow rate of urine by 89.8%, normalization of perfusion parameters and the index of microcirculation efficiency.
CONCLUSIONS: The results of the study showed that the use of Prostatex in the complex treatment of chronic bacterial prostatitis patients has a positive effect on the main symptoms of chronic prostatitis, significantly reducing pain, urination disorders and improving sexual function. This therapy helps to reduce the volume of the prostate and the volume of residual urine, restores microcirculation in the prostate gland and can be recommended in this category of patients.
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##article.viewOnOriginalSite##About the authors
Alexandr I. Neymark
Altai State Medical University
Email: neimark.a@mail.ru
ORCID iD: 0000-0002-5741-6408
SPIN-code: 4528-7765
Scopus Author ID: 7102411541
Doc. Sci. (Med.), Professor, Head of the Department of Urology and Andrology with a Course of Additional Professional Education
Russian Federation, 40, Lelina av., 656038, Barnaul, Altai RegionAndrei V. Davydov
Altai State Medical University
Email: andre1763@mail.ru
ORCID iD: 0000-0001-8212-2623
SPIN-code: 2423-1090
Doc. Sci. (Med.), Professor of the Department of Urology and Andrology with Course of Additional Professional Education
Russian Federation, 40, Lelina av., 656038, Barnaul, Altai RegionIrina V. Kablova
Altai State Medical University
Author for correspondence.
Email: irina_kablova@mail.ru
SPIN-code: 7445-0380
Cand. Sci. (Med.), Associated Professor of the Department of Urology and Andrology with Course of Additional Professional Education
Russian Federation, 40, Lelina av., 656038, Barnaul, Altai RegionReferences
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