Chronic nonspecific ulcerative pancolitis complicated by polyposis

In recent years, interest in ulcerative colitis has increased significantly due to the apparent increase in morbidity in the Soviet Union and abroad. If earlier this disease was in one way or another identified with dysentery colitis, now its nosological isolation has been proven. In the literature, this type of colitis is described as "nonspecific ulcerative colitis", "idiopathic ulcerative colitis", "severe colitis", etc. Attempts to find out the etiology and pathogenesis of this suffering have so far been unsuccessful. Existing concepts point to the multifaceted pathogenesis of ulcerative colitis. The development of the disease is due to immunoallergic, bacterial, neuro-endocrine, metabolic and other changes in the body. Ulcerative colitis is considered to be a systemic disease similar to collagenosis. Ulcerative colitis occurs in people of various age groups, but more often between the ages of 20 and 50. At an older age, the prognosis is more favorable than at a young age. The disease always proceeds chronically for many years, accompanied by periodic relapses, the development of systemic complications and complications associated with intestinal damage (anemia, thrombophlebitis, hepatitis, amyloidosis, perforation, peritonitis, bleeding, polyposis, carcinoma, etc.). Since the etiology and pathogenesis of ulcerative colitis have not been clarified, the questions of rational therapy have not been resolved either.