Erythrocyte sedimentation reaction (ESR) in acute infections

Described by R. Fahrаеus and well developed recently RPE does not cease to attract the attention of clinicians as one of the subtle biological reactions. Without going into the history of this reaction, which has been described more than once, we note that its biological basis is still largely unclear to us. Despite the work of a number of researchers, among whom there are world-famous names such as Abderhalden, Michaelis, Rona, Bürker, etc., we still do not have a generally recognized theory explaining all aspects of the phenomenon in question. The most recognized is the colloidal-chemical theory, according to which the acceleration of RPE depends on the increase of positively charged globulins in blood plasma, and the deceleration depends on the increase of negatively charged albumin.