Use of drugs of pyrimidine series for the treatment of experimental immune heart lesion
- Authors: Valimukhametova D.A.1, Nurmukhametova E.B.1
-
Affiliations:
- Kazan State Medical University
- Issue: Vol 76, No 5 (1995)
- Pages: 356-359
- Section: Articles
- URL: https://bakhtiniada.ru/kazanmedj/article/view/86929
- DOI: https://doi.org/10.17816/kazmj86929
- ID: 86929
Cite item
Full Text
Abstract
By means of immunization by the mouse heart homogenate and streptococcic allergen on guinea-pigs the model of the pathologic process is reproduced where the changes of hematologic and immunologic blood indices, the clinical picture of the heart lesion are similar to the changes observed in patients with rheumatism. The use of drugs of pyrimidine series such as methyluracil and xymedone benefits the positive dynamics of blood indices and the decrease of the manifestation of pathologic changes in the heart. Xymedont is superior to methyluracil in efficacy allowind to of patients with rheumatism.
Keywords
Full Text
##article.viewOnOriginalSite##About the authors
D. A. Valimukhametova
Kazan State Medical University
Author for correspondence.
Email: info@eco-vector.com
Department of Internal Medicine №3, Department of Clinical Pharmacology, zav.- prof.
Russian Federation, KazanE. B. Nurmukhametova
Kazan State Medical University
Email: info@eco-vector.com
Department of Internal Medicine No. 3, Department of Clinical Pharmacology
Russian Federation, KazanReferences
Supplementary files
