Intravenous infusion of calcium chloride for osteoarticular tuberculosis

Clavelin et André Sicard (Presse Médicale 22 fevrier, 1928), based on the works of Weill, Guillaumin and others regarding metabolism, calcium chloride and fixation with ultraviolet rays, subjected 28 patients with severe lesions to combined treatment. The injection technique was as follows: 1-1.5% solution of crystalline, chemically pure calcium chloride, prepared ex tempore in distilled water, was injected intravenously at a solution temperature of 40 °. The first 5 injections in the amount of 50, 100, 150, 200, 250 k. See 1% solution were injected every two days: then 1.25% solution in the same doses, and at the same intervals. After 10 injections, a break for 20 days; then again 5 injections of 1.25% solution and the last 5 injections — 1.5% solution. After each injection, the patients were exposed to the illumination of the Vash's lamp, starting from 1 minute and gradually increasing the dose. Complications included hot flushes to the head, the taste of lime in the mouth, nausea, and sometimes vomiting; in this latter case, it is necessary to stop treatment. Of the 28 patients, 17 received a noticeable improvement, significantly increased in weight, 6 remained unchanged, 4 lost a little weight and 1 gave a deterioration.