On the transfer of visdout to the cerebrospinal fluid in the treatment of syphilis in connection with the doctrine of the blood-brain barrier

On the basis of numerous studies, it has been established that some substances introduced into the blood are easily detected in the cerebrospinal fluid and nervous tissue, while others circulating in the blood, even in very significant quantities, do not appear in them under normal conditions. On the contrary, all substances introduced into the joint venture. m., very quickly appear in the blood. This circumstance indicates that between the blood — on the one hand, cn. m. f. and nervous tissue — on the other hand, apparently, there is a special mechanism of a protective nature, which is able to make a choice between the substances circulating in the blood, selectively passing some and delaying others, and also quickly removing all harmful substances from the joint venture. m f., the so-called. blood-brain barrier (Stern, Gautier).