The case of abdominal delivery in acute heteroimmune drug indused thrombocytopenia

封面


如何引用文章

全文:

详细

The secondary gravida pregnant patient with uterine scar after previous cesarean section was treated with parenteral methamizol sodium due to renal colic and acute thrombocytopenia suddenly occurred. There were supposed that this condition had been drugs induced heteroimmune thrombocytopenia. The indications for planned cesarean section were breech presentation of large fetus in patient with uterine scar. However, uterine contractions appeared in 38/39 weeks and it was decided to deliver the patient urgently after appropriate preparing. The treating of severe thrombocytopenia was substitutive — thromboconcentrate and plasma transfusion and pathogenetic — using of dexamethasone and human immunoglobulin. After transfusion of one dose of thromboconcentrate and two doses of plasma the level of thrombocytes had reached of 21 × 109/л and it was decided to start cesarean section which was performed successfully in conditions of total combined anesthesia with tracheal intubation and pulmonary ventilation. The recovery of thrombocytes quantity occurred in postoperative period with continuing using of steroid therapy.

作者简介

Dmitriy Shirokov

Ott Research Institute of Obstetrics, Gynecology and Reproductology; Saint Petersburg Pavlov State Medical University; Kirov Military Medical Academy

编辑信件的主要联系方式.
Email: dm_shirokov@interzet.ru

MD. Head of the of Anesthesiology department

俄罗斯联邦, 3, Mendeleevskaya line, Saint Petersburg, 199034; 6/9, Lva Tolstogo street, St. Petersburg, 197089; 6G, Akademika Lebedeva street, Saint-Petersburg, 194044

Vyacheslav Bolotskikh

Ott Research Institute of Obstetrics, Gynecology and Reproductology

Email: docgin@yandex.ru

PhD Deputy director for medical work

俄罗斯联邦, 3, Mendeleevskaya line, Saint Petersburg, 199034

Manana Dzhanashia

Ott Research Institute of Obstetrics, Gynecology and Reproductology

Email: manana.ott@yandex.ru

MD. Head of Pregnancy Pathology Department No 2

俄罗斯联邦, 3, Mendeleevskaya line, Saint Petersburg, 199034

Dina Eremeeva

Ott Research Institute of Obstetrics, Gynecology and Reproductology

Email: dina-bikmullina@yandex.ru

MD. obstetrician-gynecologist of Pregnancy Pathology Department No 2

俄罗斯联邦, 3, Mendeleevskaya line, Saint Petersburg, 199034

Yury Korostelev

Ott Research Institute of Obstetrics, Gynecology and Reproductology; Saint Petersburg Pavlov State Medical University

Email: juko_71@mail.ru

MD. anesthesiologist

3, Mendeleevskaya line, Saint Petersburg, 199034; 6/9, Lva Tolstogo street, St. Petersburg, 197089

Irina Vartanova

Ott Research Institute of Obstetrics, Gynecology and Reproductology; Saint Petersburg Pavlov State Medical University

Email: ivartanova@mail.ru

MD. anesthesiologist

俄罗斯联邦, 3, Mendeleevskaya line, Saint Petersburg, 199034; 6/9, Lva Tolstogo street, St. Petersburg, 197089

Aleksey Blinov

Saint Petersburg Pavlov State Medical University

Email: 79046408390@yandex.ru

internist anesthesiologist

俄罗斯联邦, 6/9, Lva Tolstogo street, St. Petersburg, 197089

参考

  1. Bowersox NA, et al. Thrombocytopenia in Pregnancy. Medscape. 2016. http://emedicine.medscape.com/ article/272867-overview
  2. Ушкалова Е.А., Астахова А.В. Проблемы безопасности анальгина // Фарматека. – 2003. – № 1 (64). [Ushkalova EA, Astahova AV. Problemy bezopasnosti anal’gina. Farmateka. 2003:1(64). (In Russ).]
  3. Redondo-Pachon MD, Enriquez R, et al. Acute renal failure and severe thrombocytopenia associated with metamizole. Saudi J Kidney Dis Transpl. 2014;25(1):121-5.
  4. Kessler CM, et al. Immune Thrombocytopenic Purpura (ITP). Medscape. 2016. http://emedicine.medscape.com/article/202158-guidelines.
  5. Rajasekhar A, Gernsheimer T, et al. Clinical Practice Guide on Thrombocytopenia in Pregnancy / American Society of Hematology. Washington; 2013.
  6. Кузьмин В.Н., Серобян А.Г. Острый жировой гепатоз беременных в практике акушера-гинеколога // Лечащий врач. – 2003. – № 5 (03). [Kuz’min VN, Serobjan AG. Ostryj zhirovoj gepatoz beremennyh v praktike akushera-ginekologa. Lechashhij vrach. 2003;5(03). (In Russ).]
  7. Меликян А.Л., Пустовая Е.И., Цветаева Н.В, и др. Национальные клинические рекомендации по диагностике и лечению первичной иммунной тром боцитопении (идиопатической тромбоцитопени ческой пурпуры) у взрослых // Гематология и трансфузио логия. – 2015. – T. 60. – № 1. – C. 44–56. [Meli kyan AL, Pustovaya EI, Tsvetaeva NV, et al. National clinical recommendations for diagnosis and therapy of idiopathic thrombocytopenic purpura (primary immune thrombocytopenia) in adults. Hematology and Transfusiology. 2015;60(1):44-56 (In Russ).]
  8. Stasi R, Provan D. Management of immune thrombocytopenic purpura in adults. Mayo Clin Proc. 2004 Apr;79(4):504-22. doi: 10.4065/79.4.504
  9. Hansen RJ, Balthasar JP. Mechanisms of IVIG action in immune thrombocytopenic purpura. Clin Lab. 2004;50(3-4):133-40.
  10. Sullivan CA, Martin JN Jr. Management of the obstetric patient with thrombocytopenia. Clin Obstet Gynecol. 1995;38(3):521-34.

补充文件

附件文件
动作
1. JATS XML

版权所有 © Shirokov D.M., Bolotskikh V.M., Dzhanashia M.M., Eremeeva D.R., Korostelev Y.M., Vartanova I.V., Blinov A.E., 2017

Creative Commons License
此作品已接受知识共享署名 4.0国际许可协议的许可

Согласие на обработку персональных данных

 

Используя сайт https://journals.rcsi.science, я (далее – «Пользователь» или «Субъект персональных данных») даю согласие на обработку персональных данных на этом сайте (текст Согласия) и на обработку персональных данных с помощью сервиса «Яндекс.Метрика» (текст Согласия).