Email this article The role of antiphospholipid antibodies on the pathogenesis of habitual pregnancy loss
- Authors: Arzhanova O.N.1, Shliakhtenko T.N.1, Selkov S.А.1, Pluzhnikova T.А.1, Tishkevitch О.V.1, Fedorenko А.V.1, Shapovalova E.A.1
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Affiliations:
- Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
- Issue: Vol 51, No 2 (2002)
- Pages: 18-22
- Section: Scientific activity
- URL: https://bakhtiniada.ru/jowd/article/view/90372
- DOI: https://doi.org/10.17816/JOWD90372
- ID: 90372
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Abstract
Clinical and anamnesis analysis as well as analysis of the course and outcome of the present pregnancy was performed on 595 patients with complicated obstetrical and gynecological history (COGH) — habitual pregnancy loss, infertility, genital chronic processes. Control groupconsisted of 5O healthy women. Immunofluorescent analysis was used to reved antiphospholipid antibodies on blood plasma. Antiphospholipid antibodies were found in 42% of COGH women. No antiphospholipid antibodies were seen in the control group. In all patients of the studied groupthe course of pregnancy was accompanied with signs of threatened abortion, gestosis. 29% (p< O, O1) patients had preterm labor and spontaneous abortion occurred in 18% (p< O, O1) of cases. Perinatal mortality was 9, 8%±4, 16.
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##article.viewOnOriginalSite##About the authors
O. N. Arzhanova
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Author for correspondence.
Email: info@eco-vector.com
Department of Obstetrics and Gynecology
Russian Federation, Saint PetersburgT. N. Shliakhtenko
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
Department of Obstetrics and Gynecology
Russian Federation, Saint PetersburgS. А. Selkov
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
Department of Obstetrics and Gynecology
Russian Federation, Saint PetersburgT. А. Pluzhnikova
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
Department of Obstetrics and Gynecology
Russian Federation, Saint PetersburgО. V. Tishkevitch
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
Department of Obstetrics and Gynecology
Russian Federation, Saint PetersburgА. V. Fedorenko
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
Department of Obstetrics and Gynecology
Russian Federation, Saint PetersburgE. A. Shapovalova
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
Department of Obstetrics and Gynecology
Russian Federation, Saint PetersburgReferences
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