Sclerotic adenomyosis: a case report

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Abstract

Four hundred and fifty case histories and results of histological studies of patients who underwent surgical treatment with a diagnosis of adenomyosis and uterine fibroids were retrospectively analyzed. Of all the operated patients, the sclerotic type of adenomyosis was detected in three cases according to the histological examination, which was 0.67%. The retrospective analysis allowed us to reveal the clinical, echographic, and histological characteristics of the sclerotic type of adenomyosis in these patients.

About the authors

Maria I. Yarmolinskaya

Research Institute of Obstetrics, Gynecology, and Reproductology named after D.O. Ott

Author for correspondence.
Email: m.yarmolinskaya@gmail.com

MD, PhD, DSci (Medicine), Professor of the Russian Academy of Sciences, the Head of the Department of Endocrinology of Reproduction, the Head of the Diagnostics and Treatment of Endometriosis Center

Russian Federation, Saint Petersburg

Eduard K. Ailamazyan

Research Institute of Obstetrics, Gynecology, and Reproductology named after D.O. Ott

Email: iagmail@ott.ru

MD, PhD, DSci (Medicine), Professor, Academician of the Russian Academy of Sciences, Honoured Scholar of the Russian Federation, the Scientific Director of the Department of Obstetrics and Perinatology

Russian Federation, Saint Petersburg

Arutyun F. Arutyunyan

Sertolovskaya City Hospital

Email: h.harutyunyan76@mail.ru

MD, PhD, the Head of the Gynecological Department

Russian Federation, Sertolovo, Leningrad Region

Andrey K. Dolinskiy

Clinical Hospital of Russian Railways

Email: dolinskiy.andrey@yandex.ru

MD, PhD, the Head of the Gynecological Department

Russian Federation, Saint Petersburg

Sergey N. Gaidukov

Saint Petersburg State Pediatric Medical University

Email: gaiducovsn@yandex.ru

MD, PhD, DSci (Medicine), Professor. The Department of Obstetrics and Gynecology with the Course of Pediatric Gynecology

Russian Federation, Saint Petersburg

References

  1. Айламазян Э.К., Ярмолинская М.И., Молотков А.С., Цицкарава Д.З. Классификации эндометриоза // Журнал акушерства и женских болезней. - 2017. - Т. 66. - № 2. - С. 77-92. [Aylamazyan EK, Yarmolinskaya MI, Molotkov AS, Tsitskarava DZ. Classifications of endometriosis. Journal of obstetrics and women’s diseases. 2017;66(3):77-92. (In Russ.)]. doi: 10.17816/JOWD66277-92.
  2. Ярмолинская М.И., Айламазян Э.К. Генитальный эндометриоз. Различные грани проблемы. - СПб.: Эко-Вектор, 2017. [Yarmolinskaya MI, Aylamazyan EK. Genital’nyy endometrioz. Razlichnye grani problemy. Saint Petersburg: Eko-Vektor; 2017. (In Russ.)]
  3. Li JJ, Chung JPW, Wang S, et al. The Investigation and Management of Adenomyosis in Women Who Wish to Improve or Preserve Fertility. Biomed Res Int. 2018;2018:6832685. doi: 10.1155/2018/6832685.
  4. Gordts S, Grimbizis G, Campo R. Symptoms and classification of uterine adenomyosis, including the place of hysteroscopy in diagnosis. Fertil Steril. 2018;109(3):380-388 e381. doi: 10.1016/j.fertnstert.2018.01.006.
  5. Pistofidis G, Makrakis E, Koukoura O, et al. Distinct types of uterine adenomyosis based on laparoscopic and histopathologic criteria. Clin Exp Obstet Gynecol. 2014;41(2):113-118.

Supplementary files

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2. Fig. 1. Incidence of different types of adenomyosis (according to G. Pistofidis et al. [5])

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3. Fig. 2. Sclerotic type of adenomyosis identified during laparascopy (according to G. Pistofidis et al. [5])

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4. Fig. 3. Sclerotic type of adenomyosis. Endometriosis lesions are recognized surrounding smooth muscle fibers with bundled growth pattern. Haematoxylin and eosin stained specimens. ×10 magnification

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5. Fig. 4. Endometriosis foci within leiomyomatous tissue with a predominant stromal pattern. Haematoxylin and eosin stained specimens. ×10 magnification

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6. Fig. 5. Sclerotic type of adenomyosis with endometriosis foci within leiomyomatous tissue. Haematoxylin and eosin stained specimens. ×10 magnification

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Copyright (c) 2018 Yarmolinskaya M.I., Ailamazyan E.K., Arutyunyan A.F., Dolinskiy A.K., Gaidukov S.N.

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