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Post a Comment Antistress and antidepressant activity of a plant drug in a mild chronic stress model
- Authors: Muruev B.A.1, Gulyaev S.M.1, Shantanova L.N.1, Mondodoev A.G.1
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Affiliations:
- Institute of General and Experimental Biology of the SB RAS
- Issue: Vol 16, No 2 (2018)
- Pages: 69-73
- Section: Articles
- URL: https://bakhtiniada.ru/RCF/article/view/9168
- DOI: https://doi.org/10.17816/RCF16269-73
- ID: 9168
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Abstract
The effect of a complex herbal remedy on the function of the central nervous system in rats on a model of chronic unpredictable mild stress was studied in the present work. The level of stress disorders was determined by the behavioral responses in rats using the methods of “open field”, “elevated plus maze”, “forced swimming test” and “tail suspension model”, weights of target organs. It is established that the complex herbal remedy has adaptogenic, anti-stress and antidepressant effects.
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##article.viewOnOriginalSite##About the authors
Bair A. Muruev
Institute of General and Experimental Biology of the SB RAS
Author for correspondence.
Email: s-gulyaev@inbox.ru
Post-Graduate Student of the Laboratory of Experimental Pharmacology
Russian Federation, Ulan-UdeSergey M. Gulyaev
Institute of General and Experimental Biology of the SB RAS
Email: s-gulyaev@inbox.ru
Candidate of Medical Sciences, Senior Researcher of the Laboratory of Experimental Pharmacology
Russian Federation, Ulan-UdeLarisa N. Shantanova
Institute of General and Experimental Biology of the SB RAS
Email: s-gulyaev@inbox.ru
Doctor of Biological Sciences, head of the laboratory of biologically active substances safety
Russian Federation, Ulan-UdeAlexander G. Mondodoev
Institute of General and Experimental Biology of the SB RAS
Email: s-gulyaev@inbox.ru
Doctor of Medical Sciences, Head of the Laboratory of Experimental Pharmacology
Russian Federation, Ulan-UdeReferences
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