Целенаправленное регулирование температуры, теплый щелочной раствор перекиси водорода и разбавленные растворы местных анестетиков как факторы безопасности при обрезании
- Авторы: Ураков А.Л.1, Сагидуллина И.Р.1, Шабанов П.Д.2,3
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Учреждения:
- Ижевская государственная медицинская академия
- Институт экспериментальной медицины
- Военно-медицинская академия им. С.М. Кирова
- Выпуск: Том 23, № 2 (2025)
- Страницы: 145-157
- Раздел: Научные обзоры
- URL: https://bakhtiniada.ru/RCF/article/view/312493
- DOI: https://doi.org/10.17816/RCF677680
- EDN: https://elibrary.ru/MAGHAG
- ID: 312493
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Аннотация
Обрезание крайней плоти — старейшая хирургическая процедура, которая стала частью мусульманской и еврейской культур и проводится здоровым мальчикам и мужчинам с древних времен. Кроме этого, обрезание является хирургическим методом лечения фимоза, баланита и баланопостита, который применяется независимо от вероисповедания. Обзор литературы показал, что хирургические и медикаментозные факторы процедуры обрезания крайней плоти иногда приводят к местным осложнениям, таким как ишемия полового члена и его ампутация, раневая инфекция, кровотечение, меатальный стеноз, кожная уретральная фистула, эрозия уретры, ятрогенная гипоспадия, синяки после инъекции, воспаление, некроз и абсцесс. Указанные осложнения ухудшают эстетический результат обрезания, настроение пациентов и их родственников, а также увеличивают расходы системы здравоохранения, связанные с лечением осложнений. В связи с этим в настоящее время в приоритете стоит повышение безопасности хирургических вмешательств и лекарственных растворов следующих фармакологических групп: анестетики (средства для внутривенной анестезии), местные анестетики, детергенты (дезинфицирующие средства), антисептические и противовоспалительные средства. Именно эти лекарственные растворы чаще всего используют при обрезании. В последние годы целенаправленное изменение локальной температуры тела становится очень актуальным, поскольку гипотермия ингибирует интенсивность осложнений локального характера, повышает жизнеспособность поврежденных, ишемизированных и отсеченных тканей, а гипертермия потенцирует дезинфицирующее действие антисептиков и способствует остановке кровотечений. Показано, что риск локальных осложнений при обрезании может быть снижен с помощью инфракрасного мониторинга локальной температуры полового члена и кожи в местах введения лекарственных растворов, поскольку это обеспечивает раннее выявление локальной гипертермии при воспалении и локальной гипотермии при ухудшении кровоснабжения тканей. Было показано, что риск ишемического повреждения мягких тканей при травме и ампутации может быть снижен с помощью терапевтической гипотермии, поскольку охлаждение повышает устойчивость тканей к ишемии. Сообщалось, что риск раневой инфекции при фимозе, парафимозе, баланите и баланопостите может быть снижен при использовании антисептических пиолитиков, которые представляют собой теплые щелочные растворы перекиси водорода, а риск некроза и абсцессов после инъекции может быть снижен путем предварительного разбавления растворов лекарственных средств водой для инъекций в два или более раз.
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Александр Ливиевич Ураков
Ижевская государственная медицинская академия
Автор, ответственный за переписку.
Email: urakoval@live.ru
ORCID iD: 0000-0002-9829-9463
SPIN-код: 1613-9660
д-р. мед. наук, профессор
Россия, ИжевскИлина Рустемовна Сагидуллина
Ижевская государственная медицинская академия
Email: ildar.sagidullin@gmail.com
ORCID iD: 0009-0005-3465-2634
Россия, Ижевск
Петр Дмитриевич Шабанов
Институт экспериментальной медицины; Военно-медицинская академия им. С.М. Кирова
Email: pdshabanov@mail.ru
ORCID iD: 0000-0003-1464-1127
SPIN-код: 8974-7477
д-р мед. наук, профессор
Россия, Санкт-Петербург; Санкт-ПетербургСписок литературы
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