CLINICOROENTGENOLOGICAL AND MORPHOLOGICAL ASPECTS OF INTERSTITIAL LUNG DISEASES

Aim. To assess the clinicoroentgenological and morphological signs of fibrosing processes in the lungs in primary diagnosis of different IIP forms, as independent pulmonary intersticial diseases. Materials and methods. One hundred and thirty nine patients observed after complex examination including pathomorphological verification were diagnosed idiopathic fibrosing alveolitis (IFA). Results. Additional profound pathomorphological investigation had the following results: usual interstitial pneumonia (UIP) as IFP basis, acute interstitial pneumonia (Hamman-Rich) and nonspecific interstitial pneumonia (NSIP). It was established that peculiarities of these IIP variants were revealed both in the early and late period of disease. Simultaneously, available inflammatory pulmonary reaction with marked sclerosis, even at the late stage of disease, proves alveolitis activity. Conclusion. Essential differences, absent in clinicoroentgenological manifestations of exacerbation of pulmonary process in chronic IIP permit to consider pathomorphological method to be the main method of nosologic ILD diagnosis.

Interstitial lung disease, clinicoroentgenological and morphological signs, idiopathic fibrosing alveolitis, pathomorphological method