Post-dural puncture headache as a complication of spinal anesthesia
- Authors: Marchenko A.P.1,2, Pavlova K.A.1,2, Ratiev P.A.1
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Affiliations:
- Derzhavin Tambov State University
- Kotovsk City Clinical Hospital
- Issue: Vol 7, No 4 (2025)
- Pages: 30-38
- Section: CLINICAL MEDICINE
- URL: https://bakhtiniada.ru/2782-5019/article/view/382164
- DOI: https://doi.org/10.20310/2782-5019-2025-7-4-30-38
- EDN: https://elibrary.ru/JYFXLM
- ID: 382164
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Abstract
Post-dural puncture headache (PDPH) is a pathological condition that occurs as a complication of spinal and epidural anesthesia. The main manifestations of this condition are headache when patients are verticalized, hemodynamic disturbances, respiratory distress, and neurological manifestations. Treatment of this condition requires a comprehensive approach, using conservative and in extreme cases invasive methods. The research purpose is to study the factors and processes leading to the development of PDPH, analyze the pattern of clinical symptoms, and evaluate possible methods for the prevention and treatment of this pathological condition. Materials and methods. The study analyzed scientific publications using the keywords “anesthesiology”, “spinal anesthesia”, “neurological complications”, “pain”, and “post-dural puncture headache treatment” for the period from 2000 to 2023. For this purpose, the online resources eLibrary and PubMed with articles published over the past 15 years were used. Results. In the pathogenesis of PDPH, the main factor is cerebrospinal fluid leakage, which is the trigger for headache. PDPH is a serious but often manageable complication following dural puncture. Conclusion. A comprehensive approach to the diagnosis and treatment of PDPH will help improve the quality of life of patients who have undergone dural puncture as quickly as possible, typically by spinal anesthesia in most cases and, less commonly, epidural anesthesia (in cases of unintentional dural puncture). This approach also helps prevent this complication.
About the authors
Alexander P. Marchenko
Derzhavin Tambov State University; Kotovsk City Clinical Hospital
Author for correspondence.
Email: sashamarchen@mail.ru
ORCID iD: 0000-0002-9387-3374
Candidate of Medicine, Associate Professor of Hospital Surgery with a Course in Traumatology of Institute of Medicine and Health Protection; Head of Anesthesiology and Resuscitation Department
33 Internatsionalnaya St., Tambov 392000, Russian Federation; 24 Pionerskaya St., Kotovsk 393190, Tambov Region, Russian FederationKseniya A. Pavlova
Derzhavin Tambov State University; Kotovsk City Clinical Hospital
Email: travma68@mail.ru
ORCID iD: 0000-0003-1931-0706
Assistant of Department of Hospital Surgery with a Course in Traumatology, Institute of Medicine and Health Protection; Physician of Anesthesiology and Resuscitation Department
33 Internatsionalnaya St., Tambov 392000, Russian Federation; 24 Pionerskaya St., Kotovsk 393190, Tambov Region, Russian FederationPetr A. Ratiev
Derzhavin Tambov State University
Email: ratiev.p@mail.ru
ORCID iD: 0009-0004-6015-8632
Senior Lecturer of Hospital Surgery with a Course in Traumatology Department of Institute of Medicine and Health Protection
33 Internatsionalnaya St., Tambov 392000, Russian FederationReferences
- Shurygin I. A. Spinal Anesthesia for Caesarean Section. St. Petersburg; 2004, 193 p. (In Russian).
- Safin R.R., Gylalov R.T., Anisimov O.G., Koryachkin V.A. Influence of spinal anesthesia technique on headache and backache frequency. Prakticheskaya meditsina. 2013;(1-2):133-134. (In Russian). EDN: RLESKJ
- Ovechkin A.M., Osipov S.A. Complications of spinal anesthesia: risk factors, prevention and treatment. Intensivnaya terapiya. 2005;(3):108-113. (In Russian).
- Fesenko V.S. Postdural puncture headache: etiology, pathogenesis, manifestations. Meditsina neotlozhnykh sostoyaniy. 2015;(6):18-20. (In Russian).
- Lauriala J.J., Lostamovaara P.A., Alahuhta S. Streptococcus Salivarius meningitis after spinal anaesthesia in an infant. Anesthesiology. 1998;19:1579-1580. doi: 10.1097/00000542-199812000-00041
- Zaporozhan V.N., Tarabrin O.A., Basenko I.L., et al. Spinal Anesthesia During Surgical Delivery. Kyiv, Start Publ.; 2013. (In Russian).
- Purdy R.A. Annual Scientific Meeting – American Headache Society Washington 2011 – Highlights. Headache. 2012;52(5):845-850. doi: 10.1111/j.1526-4610.2012.02148.x
- Osipova N.A., Petrova V.V. Pain in Surgery: Means and Methods of Protection. Moscow, Mia Publ., 2013.
- Ovechkin A.M. Spinal anesthesia: what may cause failure? Regional Anesthesia and Acute Pain Management. 2009;(3):14-18. (In Russian).
- Apiliogullari S., Gok F., Duman A., Akillioglu I. Spinal needle design and size affect the incidence of postdural puncture headache in children. Paediatrics Anaesthesiol. 2010;20(2):177-182. doi: 10.1111/j.1460-9592.2009.03236.x
- Kim M., Yoon H. Comparison of post-dural puncture headache and low back pain between 23 and 25 gauge Quincke spinal needles in patients over 60 years: randomized, double-blind controlled trial. J. Nurs. Stud. 2011 Nov;48(11):1315-1322. doi: 10.1016/j.ijnurstu.2011.04.005
- Hammond E.R., Wang Z., Bhulani N. et al. Needle type and the risk of post-lumbar puncture headache in the outpatient neurology clinic. J. Neurol. Sci. 2011;306:24-28. doi: 10.1016/j.jns.2011.04.004
- Saphin R.R. Optimization of spinal anesthesia in patients of pre-school age by using preliminary ultrasound investigation. Prakticheskaya meditsina. 2016;(4):146-147. (In Russian).
- Fesenko V.S. Postdural puncture headache: etiology, pathogenesis, manifestations. International Neurological Journal. 2015;(8):15-20. (In Russian). doi: 10.22141/2224-0713.8.78.2015.78195
- Suslov V.V., Fesenko U.A., Fesenko V.S. Spinal Anesthesia and Analgesia. Kharkiv, SIM Publ.; 2013. (In Russian).
- Morgan Jr. D.E., Mikhail M.S. Clinical Anesthesiology: in 3 books. Book 3: Bunatyan A.A., ed. Postoperative Period. Intensive Care. Moscow, Binom Publ.; 2009. (In Russian).
- Shifman E.M. A Hundred Years of Headaches. Clinical Physiology of Post-Puncture Headache. Moscow, MezhExpertPress Publ.; Petrozavodsk: IntelTek Publ.; 2004, 64 p. (In Russian).
- Morgan Jr. D.E., Mikhail M.S. Clinical Anesthesiology: in 3 books. Book 1: Bunatyan A.A., ed. Equipment and Monitoring. Regional Anesthesia. Treatment of Pain. Moscow, Binom Publ.; 2008. (In Russian).
- Basurto Ona X., Martínez García L., Solà I. et al. Drug therapy for treating post-dural puncture headache. Cochrane Database Syst. Rev. 2011;(8):CD007887. doi: 10.1002/14651858.CD007887.pub2
- Alam M.R., Rahman M.A., Ershad R. Role of very short-term intravenous hydrocortisone in reducing postdural puncture headache. J. Anaesthesiol. Clin. Pharmacol. 2012;28(2):190-193. doi: 10.4103/0970-9185.94840
- Al-Metwalli R.R. Epidural morphine injections for prevention of post dural puncture headache. Anaesthesia. 2008;63(8):847-850. doi: 10.1111/j.1365-2044.2008.05494.x
- Gormley J.B. Treatment of post-spinal headache. Anesthesiology. 1960;21:565-566.
- Boonmak P., Boonmak S. Epidural blood patching for preventing and treating postdural puncture headache. Cochrane Database Syst. Rev. 2010;20(1):CD001791. doi: 10.1002/14651858.CD001791.pub2
- Nastenko O.M., Nazarenko L.G., Fesenko V.S. Zastosuvannja bloka dykrylo-pidnebinnogo vuzla dlja likuvannja pislja punkcijnogo golovnogo bolju. Bil', zneboljuvannja i intensyvna terapija. 2015;(3):35-40. (In Ukrainian).
- Cady R., Saper J., Dexter K. et al. A double-blind, placebo-controlled study of repetitive transnasalsphenopalatine ganglion blockade with Tx360 as acute treatment for chronic migraine. Headache. 2015;55(1):101-116. doi: 10.1111/head.12458
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