Mechanisms of low-temperature rehabilitation technologies. Local deep hypothermia in patients with arthritis

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Abstract

Among all pathologies of the musculoskeletal system, osteoarthritis and rheumatoid arthritis are the two most common diseases the course of which is caused by a chronic inflammatory process. The leading clinical manifestations of osteoarthritis and rheumatoid arthritis are pain and synovitis.

This review analyzes the recent data on the pathogenesis of pain syndrome and synovitis, as well as the most commonly used surgical or conservative treatment and rehabilitation methods. The technologies of use of low-temperature effects in the rehabilitation of patients with arthritis are considered. The original concept of a new method for the relief of pain and synovitis in the knee joint by using local deep hypothermia and a hypothesis of mechanisms of its action are presented.

The purpose of the review is to provide a comparative analysis of the effectiveness of various methods of therapy and rehabilitation in patients with osteoarthritis and rheumatoid arthritis, as well as to evaluate the mechanisms of local deep hypothermia in the relief of synovitis and knee pain.

About the authors

Vasily P. Tereshenkov

Peoples' Friendship University of Russia; Priorov Central institute for Trauma and Orthopedics

Email: bizuy105@rambler.ru
SPIN-code: 6364-5445

MD, Cand. Sci. (Med.)

Russian Federation, Moscow; Moscow

Oleg A. Shevelev

Peoples' Friendship University of Russia; Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology

Author for correspondence.
Email: shevelev_o@mail.ru
ORCID iD: 0000-0002-6204-1110
SPIN-code: 9845-2960

MD, Dr. Sci. (Med.), Professor

Russian Federation, Moscow; Moscow

Nikolay V. Zagorodniy

Peoples' Friendship University of Russia; Priorov Central institute for Trauma and Orthopedics

Email: zagorodniy51@mail.ru
ORCID iD: 0000-0002-6736-9772
SPIN-code: 6889-8166

MD, Dr. Sci. (Med.), Professor, Correspondent Member of Russian Academy of Sciences

Russian Federation, Moscow; Moscow

Nadezhda A. Khodorovich

Peoples' Friendship University of Russia

Email: khodorovich_na@rudn.university
ORCID iD: 0000-0002-1289-4545
SPIN-code: 6237-9153

MD, Dr. Sci. (Med.), Professor

Russian Federation, Moscow

Alexander M. Khodorovich

Peoples' Friendship University of Russia

Email: Khodorovich@mail.ru
ORCID iD: 0000-0003-2049-5015
SPIN-code: 8781-1320

MD, Cand. Sci. (Med.)

Russian Federation, Moscow

Marina V. Petrova

Peoples' Friendship University of Russia; Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology

Email: mpetrova@fnkcrr.ru
ORCID iD: 0000-0003-4272-0957
SPIN-code: 9132-4190

MD, Dr. Sci. (Med.)

Russian Federation, Moscow; Moscow

Maria A. Zhdanova

Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology

Email: mchubarova@fnkcrr.ru
ORCID iD: 0000-0001-6550-4777
SPIN-code: 4406-7802
Russian Federation, Moscow

Elias M. Mengistu

Peoples' Friendship University of Russia; Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology

Email: drmengistu@mail.ru
ORCID iD: 0000-0002-6928-2320
SPIN-code: 1387-7508
Russian Federation, Moscow; Moscow

Inna Z. Kostenkova

Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology

Email: kostenkovaie@mail.ru
SPIN-code: 1433-1690
Russian Federation, Moscow

Ekaterina O. Sheveleva

Peoples' Friendship University of Russia

Email: sheveleva_eo@rudn.university
ORCID iD: 0000-0002-7024-8875
SPIN-code: 2593-2995

MD, Cand. Sci. (Med.)

Russian Federation, Moscow

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Copyright (c) 2022 Tereshenkov V.P., Shevelev O.A., Zagorodniy N.V., Khodorovich N.A., Khodorovich A.M., Petrova M.V., Zhdanova M.A., Mengistu E.M., Kostenkova I.Z., Sheveleva E.O.

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