NEW WAYS OF TREATING PERENNIAL ALLERGIC RHINITIS


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Abstract

Moscow State University of Medicine and Dentistry n.a. A.I. Evdokimov Selecting the proper treatment of perennial allergic rhinitis (PAR) today is often unsuccessful. At present, PAR is characterized by the early beginning, quite often continuously relapsing course and resistance to antiallergic therapy. Study of the mechanisms of the course of the disease creates a basis for the rational therapy that assumes impact on the composite inflammatory response, not only on allergy symptoms. Aim - to reflect the importance of a modern approach to treatment of patients with perennial allergic rhinitis. Materials and methods. For analysis we decided to conduct a comparative study of monotherapy with topical glucocorticosteroids and combined therapy consisting of topical glucocorticosteroids together with intranasal antihistamine medications. Results. The research showed that the use of the combined therapy with topical glucocorticosteroids and intranasal antihistamine medications can be effective in patients with perennial allergic rhinitis, considerably improving the quality of life.

About the authors

N P Dzhimsheleishvili

Otorhinolaryngology Department of MSUMD n. a. A.I. Evdokimov

Email: npjent@gmail.com
postgraduate student of the Otorhinolaryngology Department of MSUMD n. a. A.I. Evdokimov, Branch №1 of municipal clinical hospital n.a. E.O. Mukhin, otorhinolaryngologist. 11 Strelbischenskiy per., ap. 58, Moscow, Russia, 123317

A Yu Ovchinnikov

Otorhinolaryngology Department of MSUMD n. a. A.I. Evdokimov

PhD, Professor, head of the Otorhinolaryngology Department of MSUMD n.a. A. I. Evdokimov.

N A Miroshnichenko

Otorhinolaryngology Department of MSUMD n. a. A.I. Evdokimov

Email: mirnino@yandex.ru
PhD, professor of the Otorhinolaryngology Department of MSUMD n.a. A.I. Evdokimov.

References

  1. Seidman MD, Gurgel RK, Lin SY et al. Clinical practice guideline: allergic rhinitis executive summary. Otolaryngol Head Neck Surg. 2015;152(2):197-206
  2. Hermelingmeier KE, Weber RK, Hellmich M, Heubach CP, Mosges R. Nasal irrigation as an adjunctive treatment in allergic rhinitis: a systematic review and meta-analysis. Am J Rhinol Allergy. 2012;26(5):e119-e125
  3. Searing DA, Leung DY. Vitamin D in atopic dermatitis, asthma and allergic diseases. Immunol Allergy Clin North Am. 2010;30(3):397-409
  4. Barr JG, Al-Reefy H, Fox AT, Hopkins C. Allergic rhinitis in children [published correction appears in BMJ. 2014;(349):4923]. BMJ. 2014;(49):g4153
  5. Wheatley LM, Togias A. Clinical practice. Allergic rhinitis. N Engl J Med.2015;372(5):456-463
  6. Sur DK, Scandale S. Treatment of allergic rhinitis. Am Fam Physician. 2010;81(12):1440-1446
  7. Carr W, Bernstein J, Lieberman P, et al. A novel intranasal therapy of azelastine with fluticasone for the treatment of allergic rhinitis. J Allergy ClinImmunol. 2012;129(5):1282- 1289.e10
  8. Jurado-Palomo J, Bobolea ID, Belver, Gonzalez MT, et al. Treatment of allergic rhinitis: ARIA document, nasal lavage, antihistamines, cromones and vasoconstrictors. In: Gendeh BS, ed. Otolaryngology. New York, NY: In Tech; 2012:61-82
  9. Sastre J, Mosges R. Local and systemic safety of intranasal corticosteroids. J Investig Allergol Clin Immunol. 2012;22(1):1-12
  10. Price D, Shah S, Bhatia S, et al. A new therapy (MP29-02) is effective for the long-term treatment of chronic rhinitis. J Investig Allergol Clin Immunol. 2013;23(7):495-503
  11. Burks AW, Calderon MA, Casale T et al. Update on allergy immunotherapy: American Academy of Allergy, Asthma & Immunology/European Academy of Allergy and Clinical Immunology/PRACTALL consensus report. J Allergy Clin Immunol. 2013;131(5):1288-96.e3
  12. Solelhac G, Charpin D. Management of allergic rhinitis. F1000Prime Rep. 2014;(6):94

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Copyright (c) 2018 Dzhimsheleishvili N.P., Ovchinnikov A.Y., Miroshnichenko N.A.

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