Factors associated with the risk of developing diabetes mellitus in patients with coronary artery disease
- Authors: Lemeshko E.S.1, Rubanenko O.A.1, Davydkin I.L.1
-
Affiliations:
- Samara State Medical University
- Issue: Vol 8, No 2 (2023)
- Pages: 116-119
- Section: Cardiology
- URL: https://bakhtiniada.ru/2500-1388/article/view/131509
- DOI: https://doi.org/10.35693/2500-1388-2023-8-2-116-119
- ID: 131509
Cite item
Full Text
Abstract
Aim – to determine the factors associated with the risk of developing type 2 diabetes in patients with coronary artery disease (CAD).
Material and methods. The retrospective data sample included 181 patients hospitalized in the cardiology department of the SamSMU clinics. The patients were divided into two groups: group 1 – 122 patients without type 2 diabetes (77 (63.1%) men, median age 66.0 (59.0;75.0) years) and group 2 – 59 patients with type 2 diabetes (29 (49.2%) men, median age 69.0 (63.0;73.5) years).
Results. The statistically significant difference (p<0.05) was registered in glomerular filtration rate (GFR); no significant differences were demonstrated in other clinical indicators, including age and gender. Expectedly, the patients with type 2 diabetes had higher glucose levels. The parameters of the lipid spectrum and creatinine did not differ between the groups.
Conclusion. The factors associated with the risk of developing type 2 diabetes are high glucose concentration and reduced GFR. The application of the developed discriminant analysis model will allow to determine the risk group of type 2 diabetes in patients with coronary heart disease, which will ensure a timely control of the presented indicators.
Full Text
##article.viewOnOriginalSite##About the authors
Elizaveta S. Lemeshko
Samara State Medical University
Author for correspondence.
Email: lizochka.lemeshko@mail.ru
ORCID iD: 0000-0003-3989-389X
student
Russian Federation, SamaraOlesya A. Rubanenko
Samara State Medical University
Email: o.a.rubanenko@samsmu.ru
ORCID iD: 0000-0001-9351-6177
PhD, Associate professor, Department of hospital therapy with a course of outpatient care and transfusiology
Russian Federation, SamaraIgor L. Davydkin
Samara State Medical University
Email: i.l.davydkin@samsmu.ru
ORCID iD: 0000-0003-0645-7645
PhD, Professor, Head of the Department of hospital therapy with course of outpatient care and transfusiology
Russian Federation, SamaraReferences
- Tolmacheva AA, Lozhkina NG, Maksimov VN, et al. Molecular genetic markers of myocardial infarction in combination with type 2 diabetes. Russian Journal of Cardiology. 2022;27(2S):4605. (In Russ.). [Толмачева А.А., Ложкина Н.Г., Максимов В.Н., и др. Молекулярно-генетические маркеры инфаркта миокарда в сочетании с сахарным диабетом 2 типа. Российский кардиологический журнал. 2022;27(2S):4605]. doi: 10.15829/1560-4071-2022-4605
- Mortality statistics according to Rosstat. (In Russ.). [Статистика смертности по данным Росстата]. Available at: https://rosinfostat.ru/smertnost Accessed: 5 Dec 2022.
- Mardanov BU, Kokozheva MA, Shukurov FB, et al. Сlinical and hemodynamic characteristics and coronary blood flow in patients with chronic coronary artery disease and type 2 diabetes. Russian Journal of Cardiology. 2021;26(12):4639. (In Russ.). [Марданов Б.У., Кокожева М.А., Шукуров Ф.Б., и др. Особенности клинико-гемодинамических параметров и коронарного кровотока больных хронической ишемической болезнью сердца и сахарным диабетом 2 типа. Российский кардиологический журнал. 2021;26(12):4639]. doi: 10.15829/1560-4071-2021-4639
- Selvin E, Lazo M, Chen Y, et al. Diabetes Mellitus, Prediabetes, and Incidenceof Subclinical Myocardial Damage. Circulation. 2014;16(130):1374-1383. doi: 10.1161/CIRCULATIONAHA.114.010815
- Koton S, Sang Y, Schneider ALC, et al. Trends in Stroke Incidence Rates in Older US Adults: An Update From the Atherosclerosis Risk in Communities (ARIC) Cohort Study. JAMA Neurol. 2020;77(1):109-13. doi: 10.1001/jamaneurol.2019.3258
- Simerzin VV, Fatenkov OV, Gagloeva IV, et al. Innovations in diagnostics and treatment of patients with hypertriglyceridemia. Science and Innovations in Medicine. 2017;2(1):43-51. (In Russ.). [Симерзин В.В., Фатенков О.В., Гаглоева И.В., и др. Инновации в диагностике и лечении пациентов с гипертриглицеридемиями. Наука и инновации в медицине. 2017;2(1):43-51]. doi: 10.35693/2500-1388-2017-0-1
- Slatova LN, Fedorina TA, Bormotov AV, et al. Morphological characteristics of coronary and carotid atherosclerotic plaques in patients with myocardial infarction. Science and Innovations in Medicine. 2017;2(2):15-19. (In Russ.). [Слатова Л.Н., Федорина Т.А., Бормотов А.В., и др. Морфологическая характеристика атеросклеротических бляшек коронарных и сонных артерий у пациентов с инфарктом миокарда. Наука и инновации в медицине. 2017;2(2):15-19]. doi: 10.35693/2500-1388-2017-0-2-15-19
- Gracheva SA, Klefortova II, Shamkhalova MSh. Prevalence of combined atherosclerotic vascular lesions in patients with diabetes mellitus. Diabetes mellitus. 2012;15(1):49-55. (In Russ.). [Грачева С.А., Клефортова И.И., Шамхалова М.Ш. Распространенность сочетанного атеросклеротического поражения сосудов у больных сахарным диабетом. Сахарный диабет. 2012;(15)1:49-55]. doi: 10.14341/2072-0351-5979
- Begun DN, Borshchuk EL, Leushina KV. The Model for Assessing the Risk of Cardiovascular Complications in Patients with Type 2 Diabetes Mellitus. Science and Innovations in Medicine. 2018;3(2):41-44. (In Russ.). [Бегун Д.Н., Борщук Е.Л., Леушина К.В. Модель оценки риска развития сердечно-сосудистых осложнений у больных с сахарным диабетом 2 типа. Наука и инновации в медицине. 2018;3(2):41-44]. doi: 10.35693/2500-1388-2018-0-2-41-44
Supplementary files
