关于研究对象个体特征对脑脊液电导率指标的影响
- 作者: Vavilov A.Y.1, Pozdeev A.R.1, Khalikov A.А.2, Bayandina S.M.1, Agzamov V.V.2, Pozdeyeva M.A.3
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隶属关系:
- Izhevsk State Medical Academy
- Bashkir State Medical University
- Bauman Moscow State Technical University
- 期: 卷 10, 编号 4 (2024)
- 页面: 462-473
- 栏目: 原创研究
- URL: https://bakhtiniada.ru/2411-8729/article/view/288316
- DOI: https://doi.org/10.17816/fm16178
- ID: 288316
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详细
背景。现代科学文献多次提到,在法医学专家实践中研究脑脊液对于解决诸如致命性颅脑损伤的形成时间和严重程度等重要问题具有前景。电导法作为医学中研究生物对象的客观方法之一,已经使用了相当长的时间。然而,研究对象个体特征对脑脊液电导特性的影响研究明显不足。
研究目的。研究死于颅脑损伤的对象脑脊液的电导特性,分析其与研究对象个体特征的关系,为在确定导致颅脑损伤的外力形成时间的科学研究中推广电导法提供理论依据。
材料与方法。通过实验研究了124例死于颅脑损伤及其后果的尸体脑脊液的电导特性。受试者年龄从17至93岁,损伤形成时间为0至10天。电导测量采用“AKIP RLC 6109”设备 (误差为0.1%),测量频率为0.1 kHz、1 kHz和10 kHz。研究对象的个体特征包括性别、年龄、死亡时间、血液中乙醇的存在及其浓度(‰)。
结果。研究表明,研究对象的性别对脑脊液的电导特性具有显著影响,而对象的年龄和不超过24小时的死亡时间对脑脊液电导特性无显著影响。乙醇浓度的绝对值对脑脊液电导性无显著作用,但乙醇的存在显著改变了脑脊液的电流传导能力。
结论。所研究的个体特征对脑脊液电导特性的影响在开发用于研究颅脑损伤的电导方法时应予以考虑,因为这些因素可能会改变对损伤严重程度和形成时间的评估。
作者简介
Alexey Yu. Vavilov
Izhevsk State Medical Academy
Email: izhsudmed@hotmail.com
ORCID iD: 0000-0002-9472-7264
SPIN 代码: 3275-3730
MD, Dr. Sci. (Medicine), Professor
俄罗斯联邦, IzhevksAlexey R. Pozdeev
Izhevsk State Medical Academy
Email: apozdeev@bk.ru
ORCID iD: 0000-0002-6302-5219
SPIN 代码: 2242-4828
MD, Dr. Sci. (Medicine), Assistant Professor
俄罗斯联邦, IzhevksAirat А. Khalikov
Bashkir State Medical University
Email: airat.expert@mail.ru
ORCID iD: 0000-0003-1045-5677
SPIN 代码: 1895-7300
MD, Dr. Sci. (Medicine), Professor
俄罗斯联邦, UfaSophia M. Bayandina
Izhevsk State Medical Academy
Email: bay_sofia@mail.ru
ORCID iD: 0009-0005-9888-512X
SPIN 代码: 8604-6691
俄罗斯联邦, Izhevsk
Vadim V. Agzamov
Bashkir State Medical University
编辑信件的主要联系方式.
Email: expert.sudmed@yandex.ru
ORCID iD: 0000-0001-9845-2280
SPIN 代码: 2601-5485
俄罗斯联邦, Ufa
Maria A. Pozdeyeva
Bauman Moscow State Technical University
Email: mashapozdeeva5@gmail.com
ORCID iD: 0009-0007-6403-9886
SPIN 代码: 4731-6769
俄罗斯联邦, Moscow
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