Comparative analysis of methods of diagnosis of chronic fetal hypoxia using clinical epidemiology tests

The purpose of the study was to estimate the diagnostic value of different methods of diagnosis of chronic fetal hypoxia, to select the most informative ones and to optimize obstetric tactics. In a randomized prospective study chronic fetal hypoxia was revealed in 216 pregnant women in the group of high risk of developing severe placental insufficiency using diagnostic tests and taking into account the fetal daily rhythmostasis. Retrospectively, we used diagnostic tests of clinical epidemiology to calculate sensitivity, specificity, positive and negative predictive values of the results, the diagnostic accuracy of methods for diagnosing chronic fetal hypoxia, taking into consideration the histological verification of the diagnosis of placental insufficiency and the blood pH determination in the umbilical artery (blood was obtained before the first breath). The study showed that a complex approach to the diagnosis of chronic fetal hypoxia with placental insufficiency, taking into account the fetal daily rhythmostasis, has the greatest diagnostic value in comparison with the other methods.

chronic fetal hypoxia, placental insufficiency, daily rhythmostasis, evidence based medicine