Some aspects of prevalence and intrafamilial transmission of Helicobacter pylori among population of the Republic of Armenia

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Abstract

Helicobacter pylori (HP) continues to be a serious public health issue worldwide, causing significant morbidity and mortality due to peptic ulcer disease and stomach cancer. This study was conducted to investigate the prevalence and intrafamilial transmission of HP infection among the population of Armenia. Materials and methods. In this study, the immunochromatographic method was used to detect HP microorganisms in stool samples. Results. The average age of the patients tested for HP was 29.9±2.0 years, with an age range from 2 months to 75 years. The study included 316 female patients, of whom 37.7% (95% CI: 32.4–43.0) tested positive for HP microorganisms, and 180 male patients, of whom 39.4% (95% CI: 32.3–46.5) tested positive. The highest prevalence of infection was observed in the following age groups: 50–59 years (65.1%), 40–49 years (47.1%), 30–39 years (41.1%), 20–29 years (40.4%), and 60–69 years (40.0%). Conclusion. Our research on patients with inflammatory diseases of the upper gastrointestinal tract, their family members, and others revealed a high infection rate of HP across all age groups. The study demonstrated a significant prevalence of HP infection among the population of Armenia, indicating a high likelihood of intrafamilial transmission.

About the authors

A. V. Tsakanyan

National Center of Disease Control and Prevention, Ministry of Health Republic of Armenia

Email: nikolyan.sona@gmail.com

PhD (Medicine), Senior Researcher of Microbiology Laboratory

Armenia, Yerevan

H. Sh. Akinyan

National Center of Disease Control and Prevention, Ministry of Health Republic of Armenia

Email: tsakanyananaida@gmail.com

MS, Subsidiary Researcher, Microbiologist

Armenia, Yerevan

T. S. Khachatryan

National Center of Disease Control and Prevention, Ministry of Health Republic of Armenia

Email: tsakanyananaida@gmail.com

PhD (Medicine), Senior Researcher of Reference Laboratory Center

Armenia, Yerevan

A. V. Margaryan

National Center of Disease Control and Prevention, Ministry of Health Republic of Armenia

Email: tsakanyananaida@gmail.com

PhD (Medicine), Senior Researcher of Reference Laboratory Center

Armenia, Yerevan

G. G. Melik-Andreasyan

National Center of Disease Control and Prevention, Ministry of Health Republic of Armenia

Author for correspondence.
Email: tsakanyananaida@gmail.com

DSc (Medicine), Professor, Deputy Director of Reference Laboratory Center

Armenia, Yerevan

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