Comparative analysis of the results of multispiral computed tomography using color mapping and magnetic resonance imaging in the diagnosis of acute hematogenous osteomyelitis in children
- Authors: Pozdnyakov A.V.1, Svarich V.G.2,3, Lyurov D.A.4,5
-
Affiliations:
- Saint Petersburg State Pediatric Medical University
- Republican Children’s Clinical Hospital
- Pitirim Sorokin Syktyvkar State University
- Republican Children’s Hospital
- Pitirim Sorokin Syktyvkar state University
- Issue: Vol 13, No 4 (2023)
- Pages: 503-511
- Section: Original Study Articles
- URL: https://bakhtiniada.ru/2219-4061/article/view/249860
- DOI: https://doi.org/10.17816/psaic1571
- ID: 249860
Cite item
Full Text
Abstract
BACKGROUND: Although acute hematogenous osteomyelitis is considered a fairly well-studied disease, several articles emphasize that the frequency of diagnostic errors remains quite high. The clinical presentation of acute hematogenous osteomyelitis largely depends on its reactivity and localization. The latter has features of the clinical course in children of different age groups. Osteomyelitis can be difficult to detect because of the variability and nonspecificity of symptoms and physical and laboratory parameters. Rapid diagnosis is crucial for successful disease outcomes because untimely treatment increases the number of complications. Therefore, visualization should be aimed at early diagnosis and, ultimately, successful treatment.
AIM: This study aimed to evaluate the informative value of magnetic resonance imaging and multispiral computed tomography (MSCT) in the diagnosis of the intramedullary phase of acute hematogenous osteomyelitis as its earliest stage.
MATERIALS AND METHODS: Thirty patients suspected with acute hematogenous osteomyelitis underwent magnetic resonance imaging and MSCT using color mapping techniques and X-ray density assessment. At the final stage of the diagnostic algorithm, osteotonometry was performed. The contents of the bone marrow canal were taken for microbiological and bacteriological studies.
RESULTS: In the intramedullary phase of acute hematogenous osteomyelitis, magnetic resonance imaging and MSCT revealed signs of bone marrow edema in 96% of the cases. The sensitivity of magnetic resonance imaging was 96%, the same as that of MSCT; however, the specificity was significantly lower than that of MSCT using the color mapping method and X-ray density assessment, which was 67% and 83%, respectively (p < 0.05).
DISCUSSION: In recent years, the role of computed tomography in the diagnosis of acute hematogenous osteomyelitis has received considerable recognition in pediatric surgical practice, and MSCT with color mapping and X-ray density assessment in the diagnosis of acute hematogenous osteomyelitis in children has been used relatively recently. Simultaneously, many researchers have reported the high informativeness of MSCT in the diagnosis of acute hematogenous osteomyelitis.
CONCLUSIONS: The intramedullary phase of acute hematogenous osteomyelitis according to magnetic resonance imaging and MSCT indicates bone marrow edema as its earliest stage. According to the data of the present study, MSCT using color mapping and X-ray density assessment has high specificity and can be used with MRI as the main method for diagnosing the intramedullary phase of acute hematogenous osteomyelitis.
Full Text
##article.viewOnOriginalSite##About the authors
Alexander V. Pozdnyakov
Saint Petersburg State Pediatric Medical University
Email: pozdnyakovalex@yandex.ru
ORCID iD: 0000-0002-1110-066X
SPIN-code: 1000-6408
MD, Dr. Sci. (Med.), Professor
Russian Federation, Saint PetersburgVyacheslav G. Svarich
Republican Children’s Clinical Hospital; Pitirim Sorokin Syktyvkar State University
Author for correspondence.
Email: svarich61@mail.ru
ORCID iD: 0000-0002-0126-3190
SPIN-code: 7684-9637
MD, Dr. Sci. (Med.)
Russian Federation, Syktyvkar; SyktyvkarDenis A. Lyurov
Republican Children’s Hospital; Pitirim Sorokin Syktyvkar state University
Email: denis_liurov@mail.ru
ORCID iD: 0000-0002-8818-0055
SPIN-code: 2687-8324
Russian Federation, Syktyvkar; Syktyvkar
References
- Shamsiev ZhA, Shamsiev AM, Makhmudov ZM. To the question of early diagnosis of acute hematogenous osteomyelitis of bones of the hip joint in children. Pediatric surgery. 2018;22(2):83–88.
- Sazhin AA, Rumyantseva GN. Features of the course of metaepiphyseal osteomyelitis in young children. Tver Medical Journal. 2017;(3):70–72. (In Russ.)
- Lyurov DA, Svarich VG, Рozdnjakov AV. Optimization techniques for early diagnosis of acute gematogennogo osteomyelitis in children. Visualization in medicine. 2020;2(3):13–21.
- Mamatov AM, Abhadylykov ZA, Kamshibekov UA, Boronbaeva EA. Treatment of septic forms of acute osteomyelitis in children. Bulletin of Science and Practice. 2018;4(11):97–100. doi: 10.5281/zenodo.1488116
- Rumyantseva GN, Gorshkov AY, Sergeechev SP, Mikhailova SI. Acute metaepiphyseal osteomyelitis in young children, peculiarities of course and diagnosis. Modern problems of science and education. 2017;(4):41.
- Arnold JC, Bradley JC. Osteoarticular infections in children. Infect Dis Clin North Am. 2015;29(3):557–574. doi: 10.1016/j.idc.2015.05.012
- Eshonova TD. Acute hematogenous osteomyelitis in children. Pediatria n.a. after G.N. Speransky. 2016;95(2):146–152.
- Karmazanovsky GG. Assessment of diagnostic significance of the method (sensitivity, specificity, overall accuracy). Annals of HPB Surgery. 1997;2:139–142.
- Rumyantseva GN, Gorshkov AY, Sergeechev SP, Mikhailova SI. Methods of radial diagnostics in acute metaepiphyseal osteomyelitis. Pediatric surgery. 2019;23(1S3):56. (In Russ.)
- Minaev SV, Filipieva NV, Leskin VV, et al. Radiological methods in diagnostics of acute haematogenous osteomyelitis in children. Doctor.Ru. 2018;(5):32–36. doi: 10.31550/1727-2378-2018-149-5-32-36
- Simpfendorfer CS. Radiologic approach to musculoskeletal infections. Infect Dis Clin North Am. 2017;31(2):299–324. doi: 10.1016/j.idc.2017.01.004
- James DC, Gail JH, Sheldon LK, et al. Feigin and Cherry’s textbook of pediatric infectious diseases. 7th edition. Elsiver, 2014. Vol. 55. Р. 711–727.
- Pugmire BS, Shailam R, Gee MS. Role of MRI in the diagnosis and treatment of osteomyelitis in pediatric patients. World J Radiol. 2014;6(8):530–537. doi: 10.4329/wjr.v6.i8.530
- Lee YJ, Sadigh S, Mankad K, et al. The imaging of osteomyelitis. Quant Imaging Med Surg. 2016;6(2):184–198. doi: 10.21037/qims.2016.04.01
- Dartnell J, Ramachandran M, Katchburian M. Haematogenuos acute and subacute paediatric osteomyelitis. A systematic review of the literature. J Bone Joint Surg. 2012;94-B(5):584–595. doi: 10.1302/0301-620X.94B5.28523
- Mikhailova SI, Rumyantseva GN, Yusufov AA, et al. Methods of radiation diagnostics of acute hematogenous osteomyelitis in children of different age groups. Modern problems of science and education. 2020;(2):148. doi: 10.17513/spno.29711
- Strelkov NS, Razin MF. Hematogenic osteomyelitis in children. Moscow: GEOTAR-Media., 2018. 160 p. (In Russ.)
Supplementary files
