Effect of nitrendipine on Ca2+-homeostasis of neurons and activity of cytotoxic factors in Alzheimer's disease
- Authors: Astashkin E.I1
-
Affiliations:
- I. M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation
- Issue: Vol 19, No 10 (2017)
- Pages: 137-142
- Section: Articles
- URL: https://bakhtiniada.ru/2075-1753/article/view/94956
- DOI: https://doi.org/10.26442/2075-1753_19.10.137-142
- ID: 94956
Cite item
Full Text
Abstract
Full Text
##article.viewOnOriginalSite##About the authors
E. I Astashkin
I. M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation
Email: ast-med@mail.ru
119991, Russian Federation, Moscow, ul. Trubetskaia, d. 8, str. 1
References
- Serrano-Pozo A, Frosch M.P, Masliah E, Hyman B.T. Neuropathological alterations in Alzheimer disease. Cold Spring Harb Perspect Med 2011; 1: a006189.
- Magi S, Castaldo P, Macri M.L. et al. Intracellular calcium disregulation: implications for Alzheimer’s Disease. Hindawi Publishing Corporation. BioMed Res Int Volume 2016; Article ID 6701324.
- Forette F et al. Prevention of dementia in randomised double-blind placebo-controlled Systolic Hypertension in Europe (Syst-Eur) trial. Lancet 1998; 352: 1347-51.
- Fritze J, Walden J et al. Clinical findings with nimodipine in dementia: test of the calcium hypothesis. J Neural Transm Suppl 1995; 46: 439-53.
- Tollefson G.D. Short-term effects of the calcium channel blocker nimodipine (Bay-e-9736) in the management of primary degenerative dementia. Biol Psychiatry 1990; 27: 1133-42.
- Anekonda Th.S, Quinn J.F, Harris Ch. et al. L-type voltage-gated calcium channel blockade with isradipine as a therapeutic strategy for Alzheimer’s disease. Neurobiol Dis 2011 ; 41 (1) : 62-70.
- Woltjer R.L. Role of glutathione in intracellular amyloid-alpha precursor protein/carboxy- terminal fragment aggregation and associated cytotoxicity. J Neurochem 2005; 93: 1047-56.
- Woltjer R.L. et al. Effects of chemical chaperones on oxidative stress and detergent-insoluble species formation following conditional expression of amyloid precursor protein carboxy-terminal fragment. Neurobiol Dis 2007; 25: 427-37.
- Wadsworth T.L et al. Evaluation of coenzyme Q as an antioxidant strategy for Alzheimer's disease. J Alzheimers Dis 2008; 14: 225-34.
- Demuro A, Parker I, Stutzmann G.E. Calcium signaling and amyloid toxicity in Alzheimer disease. J Biol Chem 2010; 285 (17): 12463-8.
- Berridge M.J. Calcium hypothesis of Alzheimer’s disease. Pflugers Arch - Eur J Physiol. doi: 10.1007/s00424-009-0736-1
- Kawahara M, Negishi-Kato M, Sadakane Y. Calcium dyshomeostasis and neurotoxicity of Alzheimer's beta-amyloid protein. Expert Rev Neurother 2009; 9 (5): 681-93.
- Zhang Y, Li P, Feng J, Wu M. Dysfunction of NMDA receptors in Alzheimer’s disease. Neurol Sci 2016; 37: 1039-47.
- Toda T, Noda Y, Ito G et al. Presenilin-2 mutation causes early amyloid accumulation and memory impairment in a transgenic mouse model of Alzheimer’s disease. Hindawi Publishing Corporation J Biomed Biotechnol Volume 2011; Article ID 617974.
- Tu H, Nelson O, Bezprozvanny A et al. Presenilins Form ER Ca2* Leak Channels, a Function Disrupted by Familial Alzheimer's Disease-Linked Mutations. Alzheimers Dis 2009; 16 (2) : 211-24.
- Xu X. g-Secretase Catalyzes Sequential Cleavages of the AbPP Transmembrane Domain. J Cell 2006; 126 (5): 981-93.
- Supnet Ch, Bezprozvanny I. The dysregulation of intracellular calcium in Alzheimer disease. Cell Calcium 2010; 47 (2): 183-9.
- Nussbaum J.M, Seward M.E, Bloom G.S. Alzheimer disease. A tale of two prions. Prion 2013; 7 (1): 14-9.
- Shu-Ming Huang, Akihiro Mouri, Hideko Kokubo et al. Neprilysin-sensitive synapse-associated amyloid-b peptide oligomers impair neuronal plasticity and cognitive function. J Biol Chem 2006; 281 (26): 17941-51.
- Eisele Y, Monteiro C, Fearns C et al. Targeting Protein Aggregation for the Treatment of Degenerative Diseases. Nat Rev Drug Discov 2015; 14 (11): 759-80.
- Forette F et al. The prevention of dementia with antihypertensive treatment: new evidence from the Systolic Hypertension in Europe (Syst-Eur) study. Arch Intern Med 2002; 162: 2046-52.
- Hanon O, Forette F. Prevention of dementia: lessons from SYST-EUR and PROGRESS. J Neurol Sci 2004; 226: 71-4.
- Paris D, Bachmeier C, Patel N. Selective antihypertensive dihydropyridines lower Ab accumulation by targeting both the production and the clearance of Ab across the Blood-Brain Barrier. Mol Med 2011; 17 (3-4): 149-62.
Supplementary files
