Possibilities of symptomatic treatment of skin itching
- Authors: Kholodilova N.A.1, Monakhov K.N.1
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Affiliations:
- Pavlov First Saint Petersburg State Medical University
- Issue: Vol 31, No 9 (2024)
- Pages: 112-116
- Section: Dermatology/allergology
- URL: https://bakhtiniada.ru/2073-4034/article/view/294175
- DOI: https://doi.org/10.18565/pharmateca.2024.9.112-116
- ID: 294175
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Abstract
Background. Skin itching is a dominant symptom in most dermatoses. It has a negative impact on the general condition of the patient, his working capacity, social communication, which significantly reduces the quality of life and requires active therapy.
Objective. Evaluation of the antipruritic and anti-inflammatory effects of the Fleming’s ointment in various itchy dermatoses.
Methods. An open comparative study involving 30 patients with atopic dermatitis, eczema and skin itching of other etiologies was conducted. For rashes accompanied by itching, it was recommended to apply Fleming’s ointment 2–3 times a day together with basic skin care products. The intensity of skin itching, the time of onset of the antipruritic effect against the background of the study drug, its duration, the anti-inflammatory effect of the drug, as well as its safety were assessed in patients.
Results. The use of Fleming’s ointment in patients with itchy dermatoses made it possible to reduce the intensity of skin itching in most patients (26 people) on the 3rd day of treatment. The anti-inflammatory effect of the drug was noted in most patients (in 24 people) on the 10th day of the study. By the end of the study, according to the doctor’s assessment, 26 patients showed significant improvement from the therapy. No side effects were detected in any patient.
Conclusion. The results of the study allow to recommend Fleming’s ointment as an effective and safe remedy for the treatment of skin itching in dermatoses.
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##article.viewOnOriginalSite##About the authors
N. A. Kholodilova
Pavlov First Saint Petersburg State Medical University
Author for correspondence.
Email: kholodilova83@list.ru
ORCID iD: 0000-0002-7765-7487
SPIN-code: 7601-0687
Cand. Sci. (Med.), Associate Professor
Russian Federation, Saint PetersburgK. N. Monakhov
Pavlov First Saint Petersburg State Medical University
Email: kholodilova83@list.ru
ORCID iD: 0000-0002-8211-1665
Russian Federation, Saint Petersburg
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