Intensification of glucose-lowering therapy for type 2 diabetes mellitus using insulin degludec: clinical case analysis
- Authors: Elsukova O.S.1,2
-
Affiliations:
- Kirov State Medical University
- Kirov Clinical Hospital № 7 n.a. V.I. Yurlova
- Issue: Vol 30, No 12 (2023)
- Pages: 132-137
- Section: Clinical case
- URL: https://bakhtiniada.ru/2073-4034/article/view/275644
- DOI: https://doi.org/10.18565/pharmateca.2023.12.132-137
- ID: 275644
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Abstract
The article discusses a clinical case of intensification of glucose-lowering therapy with insulin degludec in a patient with type 2 diabetes mellitus (DM2); who did not achieve glycemic control goals despite the use of a combination of three glucose-lowering drugs: metformin; empagliflozin and semaglutide. Fasting and postprandial glycemia was more than 10 mmol/l; the glycated hemoglobin level was 10.4%. In addition; the time above the target range was 85%; and no hypoglycemic conditions were recorded. After intensifying hypoglycemic therapy with insulin degludec; a significant improvement in glycemic control was noted: fasting glucose was 5.4–6.2 mmol/l; postprandial – up to 10 mmol/l; the time in the target range; according to flash data. monitoring was 99%; no hypoglycemic conditions were noted.
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##article.viewOnOriginalSite##About the authors
Olga S. Elsukova
Kirov State Medical University; Kirov Clinical Hospital № 7 n.a. V.I. Yurlova
Author for correspondence.
Email: oselsukova@mail.ru
ORCID iD: 0000-0002-2341-9491
Cand. Sci. (Med.), Associate Professor at the Department of Hospital Therapy, Head of the Endocrinology Department
Russian Federation, Kirov; KirovReferences
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