Implementing digital technologies in microbiological monitoring and antimicrobial resistance assessment in intensive care units
- Authors: Mironenko O.V.1,2,3, Buzinov R.V.4, Tovanova A.A.1,2, Kovalenko I.Y.5, Petrova E.A.6, Selnitseva V.V.7, Podboronov M.I.3, Butskaya M.Y.7
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Affiliations:
- North-Western State Medical University n.a. I.I. Mechnikova
- Saint-Petersburg State University
- My Medical Center
- Northwest Hygiene and Public Health Research Center
- Dental clinic No. 32, St. Petersburg
- City Hospital No. 26, St. Petersburg
- City Multidisciplinary Hospital No. 2, St. Petersburg
- Issue: Vol 32, No 11 (2025)
- Pages: 822-831
- Section: ORIGINAL STUDY ARTICLES
- URL: https://bakhtiniada.ru/1728-0869/article/view/362970
- DOI: https://doi.org/10.17816/humeco689971
- EDN: https://elibrary.ru/GLKXMS
- ID: 362970
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Full Text
Abstract
BACKGROUND: Healthcare-associated infections remain a major challenge of modern medical practice, with multidrug-resistant strains representing the most clinically significant pathogens. A central problem is the widespread dissemination of Klebsiella pneumoniae in intensive care units. This prevalence is associated with the severe condition of patients, for whom infection with multidrug-resistant strains exacerbates the underlying disease, extends the duration of therapy, and results in a significant economic burden. Systematic microbiological monitoring and evaluation of the antimicrobial resistance of strains isolated from patient biological specimens are key elements of healthcare-associated infection control in inpatient healthcare settings.
AIM: This work aimed to perform a comparative analysis of the microbiological landscape and antimicrobial resistance patterns of multidrug-resistant isolates using modern digital technologies in the intensive care and cardiac intensive care units of two multidisciplinary hospitals in Saint Petersburg.
METHODS: A retrospective analysis was conducted using microbiological surveillance data from the intensive care units and cardiac intensive care units of two multidisciplinary hospitals in Saint Petersburg for 2024. The obtained data were processed using the analytical software WHONET and the online platform AMRCloud.
RESULTS: ESCAPE pathogens were the predominant microorganisms isolated from sputum and bronchoalveolar lavage in both intensive care units and cardiac intensive care units. A statistically significant higher level of resistance among these isolates was observed in intensive care units compared with cardiac intensive care units. To analyze the prevalence of ventilator-associated pneumonia, we calculated stratified epidemiological indicators. The results were consistent with the published data.
CONCLUSION: Regular microbiological monitoring is a key tool for controlling healthcare-associated pathogens and tracking their antimicrobial resistance in a hospital setting. This monitoring enables a timely response to shifts in the epidemiological situation, including changes in microbial profile, the emergence of new strain associations, and their resistance to antibacterial agents. Such work is inherently linked to the rapid analysis of large datasets, which necessitates the development of new digital technologies for integration into hospital information systems.
About the authors
Olga V. Mironenko
North-Western State Medical University n.a. I.I. Mechnikova; Saint-Petersburg State University; My Medical Center
Email: miroolga@yandex.ru
ORCID iD: 0000-0002-1484-8251
SPIN-code: 9368-7627
MD, Dr. Sci. (Medicine), Professor
Russian Federation, St. Petersburg; St. Petersburg; St. PetersburgRoman V. Buzinov
Northwest Hygiene and Public Health Research Center
Email: r.buzinov@s-znc.ru
ORCID iD: 0000-0002-8624-6452
SPIN-code: 8849-3830
MD, Dr. Sci. (Medicine)
Russian Federation, St. PetersburgAnna A. Tovanova
North-Western State Medical University n.a. I.I. Mechnikova; Saint-Petersburg State University
Author for correspondence.
Email: ann.tovan@bk.ru
ORCID iD: 0000-0002-4137-8259
SPIN-code: 7687-4489
MD, Cand. Sci. (Medicine)
Russian Federation, St. Petersburg; St. PetersburgIgor Yu. Kovalenko
Dental clinic No. 32, St. Petersburg
Email: igorkovalenko022@yandex.ru
SPIN-code: 4643-5110
Russian Federation, St. Petersburg
Elena A. Petrova
City Hospital No. 26, St. Petersburg
Email: petrova_epid@mail.ru
SPIN-code: 8923-3499
Russian Federation, St. Petersburg
Victoria V. Selnitseva
City Multidisciplinary Hospital No. 2, St. Petersburg
Email: selavik@mail.ru
ORCID iD: 0009-0002-9486-2519
Russian Federation, St. Petersburg
Mikhail I. Podboronov
My Medical Center
Email: podboronov.misha@yandex.ru
ORCID iD: 0000-0002-5727-8965
SPIN-code: 2352-2471
Russian Federation, St. Petersburg
Maria Yu. Butskaya
City Multidisciplinary Hospital No. 2, St. Petersburg
Email: butskaya.masha@yandex.ru
ORCID iD: 0000-0003-0933-7972
SPIN-code: 3602-8316
Russian Federation, St. Petersburg
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