Indicators of local oral immunity in users of new types of tobacco products
- Авторлар: Ostrovskaya I.G.1, Abramova M.Y.1, Parshkov V.V.1, Mamatsashvili V.G.1
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Мекемелер:
- Russian University of Medicine
- Шығарылым: Том 27, № 7 (2024)
- Беттер: 40-45
- Бөлім: Medical chemistry
- URL: https://bakhtiniada.ru/1560-9596/article/view/260585
- DOI: https://doi.org/10.29296/25877313-2024-07-06
- ID: 260585
Дәйексөз келтіру
Ашық рұқсат
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Аннотация
Introduction. The organs and structures of the oral cavity are among the first to come into contact with the aerosol when using elec- tronic cigarettes and heated-tobacco products, and some of the aerosol components enter various biological fluids of the mouth, inevi- tably provoking a response of the body to external influences. One of the markers of the response are immunoglobulins, and their analysis is intended to help in studying the effect of electronic cigarettes and heated-tobacco products on humans.
Objective. The aim of the study was to estimate changes in immunoglobulins A, G and M of gingival fluid, oral fluid and saliva among users of new types of tobacco products.
Material and methods. The study included 4 groups of 5 people each: regular cigarette smokers, e-cigarette users, users of tobacco heating systems and non-smokers. For laboratory studies, gingival fluid, saliva and oral fluid were taken from the subjects.
Results. Various changes in the concentration of immunoglobulins relative to the control group were observed in all groups of smok- ing patients.
Conclusion. The results may indicate inhibition of the function of local immunity both when exposed to tobacco smoke and when ex- posed to aerosol of heated-tobacco products or electronic cigarettes, which increases the vulnerability of organs and structures of the oral cavity to pathogenic microorganisms.
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##article.viewOnOriginalSite##Авторлар туралы
I. Ostrovskaya
Russian University of Medicine
Хат алмасуға жауапты Автор.
Email: pit.vadim@mail.ru
ORCID iD: 0000-0001-6788-4945
Dr.Sc. (Med.), Professor
Ресей, st. Dolgorukovskaya 4, building 1, 127006, MoscowM. Abramova
Russian University of Medicine
Email: pit.vadim@mail.ru
ORCID iD: 0000-0001-7762-1540
Dr.Sc. (Med.), Professor
Ресей, st. Dolgorukovskaya 4, building 1, 127006, MoscowV. Parshkov
Russian University of Medicine
Email: pit.vadim@mail.ru
ORCID iD: 0009-0005-0074-3140
Post-graduate Student
Ресей, st. Dolgorukovskaya 4, building 1, 127006, MoscowV. Mamatsashvili
Russian University of Medicine
Email: pit.vadim@mail.ru
ORCID iD: 0009-0001-5571-9958
Post-graduate Student
Ресей, st. Dolgorukovskaya 4, building 1, 127006, MoscowӘдебиет тізімі
- National Center for Chronic Disease P, Health Promotion Office on S, Health. Reports of the surgeon general. In: The Health Consequences of Smoking-50 Years of Progress: A Report of the Surgeon General. Atlanta, GA: Centers for Disease Control and Prevention (US); 2014.
- Zong D., Liu X., Li J., et al. The role of cigarette smoke-induced epigenetic alterations in inflammation. Epigenetics Chromatin. 2019; 12: 65.
- Michcik A., Cichorek M., Daca A., et al. Tobacco smoking alters the number of oral epithelial cells with apoptotic features. Folia Histochem Cytobiol. 2014; 52: 60–68.
- Kinouani S., Pereira E., Tzourio C. Electronic cigarette use in students and its relation with tobacco-smoking: a cross-sectional analysis of the i-share study. Int. J. Environ. Res. Public Health. 2017; 14: 1345.
- Maj A., Kusiak A., Wojtaszek-Slominska A., et al. Electronic cigarettes use among 10–11-years old: Preliminary report. Dent. Forum. 2018; 46: 31–34.
- Smith D.M., Gawron M., Balwicki LSobczak A., et al. Exclusive versus dual use of tobacco and electronic cigarettes among adolescents in Poland, 2010–2016. Addict. Behav. 2019; 90: 341–348.
- WHO study group on tobacco product regulation: report on the scientific basis of tobacco product regulation: seventh report of a WHO study group / WHO study group on tobacco product regulation. Geneva: World Health Organization, 2019; 275 с.
- Bentley M.C., Almstetter M., Arndt D., et al. Comprehensive chemical characterization of the aerosol generated by a heated tobacco product by untargeted screening. Anal Bioanal Chem. 2020; 412(11): 2675–2685.
- St. Helen G., Jacob I.P., Nardone N., Benowitz N.L. IQOS: Examination of Philip Morris International’s claim of reduced exposure. Tob. Control. 2018; 27(Suppl.): s30–s36.
- Pisinger C., Dossing M. A systematic review of health effects of electronic cigarettes. Prev. Med. 2014; 69: 248–260. doi: 10.1016/j.ypmed.2014.10.009.
- Kaur G., Muthumalage T., Rahman I. Mechanisms of toxicity and biomarkers of flavoring and flavor enhancing chemicals in emerging tobacco and non-tobacco products. Toxicol Lett. 2018; 288: 143–155.
- Znyk M., Jurewicz J., Kaleta D. Exposure to Heated Tobacco Products and Adverse Health Effects, a Systematic Review. Int. J. Environ. Public Health. 2021; 18: 6651. doi: 10.3390/ijerph18126651.
- Giuca M.R., Pasini M., Tecco S., et al. Levels of salivary immunoglobulins and periodontal evaluation in smoking patients. BMC Immunol. 2014 Feb 6; 15: 5. doi: 10.1186/1471-2172-15-5.
- Nigar S., Hassan S., Maqsood A., et al. An assessment of unstimulated salivary flow rate, IgA and clinical oral dryness among active and passive smokers. Int J Occup Med Environ Health. 2022 Feb 15; 35(1): 39–51.
- Cichońska D., Kusiak A., Kochańska B., et al. Influence of Electronic Cigarettes on Selected Antibacterial Properties of Saliva. Int J Environ Res Public Health. 2019 Nov 12; 16(22): 4433.
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