Synthesis and Antitubercular and Antibacterial Activities of Triethylammonium 2-Acetamido-3,4,6-tri- O -acetyl-2-deoxy-D-glucopyranosyl Decyl Phosphate

B. F. Garifullin; R. R. Sharipova; A. D. Voloshina; M. A. Kravchenko; V. E. Kataev

doi:10.1134/S1070428018090117

Synthesis and Antitubercular and Antibacterial Activities of Triethylammonium 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-D-glucopyranosyl Decyl Phosphate

作者: Garifullin B.F.¹, Sharipova R.R.¹, Voloshina A.D.¹, Kravchenko M.A.², Kataev V.E.¹
隶属关系:
1. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
2. Ural Research Institute of Phthisiopulmonology
期: 卷 54, 编号 9 (2018)
页面: 1333-1336
栏目: Article
URL: https://bakhtiniada.ru/1070-4280/article/view/218893
DOI: https://doi.org/10.1134/S1070428018090117
ID: 218893

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Phosphorylation of 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-D-glucose at the anomeric hydroxy group gave previously unknown triethylammonium 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-D-glucopyranosyl phosphonate, and successive treatment of the latter with decan-1-ol and aqueous iodine afforded triethylammonium 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-glucopyranosyl phosphate.