Email this article Synthesis of fluoroquinoxalin-2(1H)-one derivatives containing substituents in the pyrazine and benzene fragments
- Authors: Azev Y.A.1, Ermakova O.S.1, Berseneva V.S.1, Bakulev V.A.1, Ezhikova M.A.2, Kodess M.I.1,2
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Affiliations:
- Ural Federal University
- Postovskii Institute of Organic Synthesis, Ural Branch
- Issue: Vol 53, No 1 (2017)
- Pages: 90-95
- Section: Article
- URL: https://bakhtiniada.ru/1070-4280/article/view/215652
- DOI: https://doi.org/10.1134/S107042801701016X
- ID: 215652
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Abstract
6,7-Difluoroquinoxalin-2-one reacted with indoles, 5,5-dimethylcyclohexane-1,3-dione, 3-methyl-1-phenyl-1H-pyrazol-5(4H)-one, resorcinol, and pyrogallol on heating in acetic acid to give products of hydrogen substitution in the heterocyclic fragment. Heating of 6,7-difluoro-3-(1H-indol-3-yl)quinoxalin-2(1H)-ones with N-methylpiperazine gave the corresponding 7-(4-methylpiperazin-1-yl) derivatives.
About the authors
Yu. A. Azev
Ural Federal University
Author for correspondence.
Email: azural@yandex.ru
Russian Federation, ul. Mira 19, Yekaterinburg, 620002
O. S. Ermakova
Ural Federal University
Email: azural@yandex.ru
Russian Federation, ul. Mira 19, Yekaterinburg, 620002
V. S. Berseneva
Ural Federal University
Email: azural@yandex.ru
Russian Federation, ul. Mira 19, Yekaterinburg, 620002
V. A. Bakulev
Ural Federal University
Email: azural@yandex.ru
Russian Federation, ul. Mira 19, Yekaterinburg, 620002
M. A. Ezhikova
Postovskii Institute of Organic Synthesis, Ural Branch
Email: azural@yandex.ru
Russian Federation, ul. S. Kovalevskoi/Akademicheskaya 22/20, Yekaterinburg, 620990
M. I. Kodess
Ural Federal University; Postovskii Institute of Organic Synthesis, Ural Branch
Email: azural@yandex.ru
Russian Federation, ul. Mira 19, Yekaterinburg, 620002; ul. S. Kovalevskoi/Akademicheskaya 22/20, Yekaterinburg, 620990
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