Enviar artigo por via de e-mail Solvent-Free Synthesis, ADME Prediction, and Evaluation of Antibacterial Activity of Novel Sulfonamide Derivatives
- Autores: Rafiee Pour Z.1, Nazifi S.M.2, Afshari Safavi A.3, Nazifi Z.S.1, Massah A.R.1,4
-
Afiliações:
- Department of Chemistry, Shahreza Branch
- Department of Medicinal Chemistry, School of Pharmacy and Pharmaceutical Sciences
- Student Research Committee, School of Health
- Razi Chemistry Research Center, Shahreza Branch
- Edição: Volume 55, Nº 6 (2019)
- Páginas: 852-859
- Seção: Review
- URL: https://bakhtiniada.ru/1070-4280/article/view/220770
- DOI: https://doi.org/10.1134/S1070428019060162
- ID: 220770
Citar
Acesso aberto
Acesso está concedido
Somente assinantes
Resumo
A series of novel sulfonamides containing a 2-amino-1,3-thiazole fragment have been synthesized using a simple and efficient method under solvent-free conditions. The obtained N-(4-sulfamoyl-1,3-thiazol-2-yl)-4-nitrobenzamides were evaluated for their antibacterial activity against S. aureus and E. coli, and in silico ADME prediction was performed to find biological behavior.
Sobre autores
Z. Rafiee Pour
Department of Chemistry, Shahreza Branch
Email: massah@iaush.ac.ir
Irã, Shahreza, Isfahan
S. Nazifi
Department of Medicinal Chemistry, School of Pharmacy and Pharmaceutical Sciences
Email: massah@iaush.ac.ir
Irã, Isfahan
A. Afshari Safavi
Student Research Committee, School of Health
Email: massah@iaush.ac.ir
Irã, Isfahan
Z. Nazifi
Department of Chemistry, Shahreza Branch
Email: massah@iaush.ac.ir
Irã, Shahreza, Isfahan
A. Massah
Department of Chemistry, Shahreza Branch; Razi Chemistry Research Center, Shahreza Branch
Autor responsável pela correspondência
Email: massah@iaush.ac.ir
Irã, Shahreza, Isfahan; Shahreza, Isfahan
Arquivos suplementares
