Three-Component Spiro Heterocyclization of Pyrrolediones, Indane-1,3-dione, and Heterocyclic Enamines

Resumo

3-Methyl-2′,5-dioxo-5′-phenyl-1′,2′,5,10-tetrahydrospiro(indeno[1,2-b]isoxazolo[4,3-e]pyridine-4,3′-pyrroles) and 2′,5-dioxo-5′-phenyl-1′,2′,5,10-tetrahydro-1H-spiro(indeno[1,2-b]pyrazole[4,3-e]pyridine-4,3′-pyrroles) are formed via three-component spiro heterocyclization of 4-(ethoxycarbonyl)-5-phenyl-1Hpyrrole-2,3-diones and indane-1,3-dione with 5-amino-3-methylisoxazole or 5-amino-1H-pyrazoles.