Enviar artigo por via de e-mail New facilities of Biginelli reaction. Synthesis of methyl 6-aryl-5-benzoyl-4-methoxy-2-oxohexahydropyrimidine-4-carboxylates
- Autores: Gein V.L.1, Gorgopina E.V.1, Zamaraeva T.M.1, Dmitriev M.V.2
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Afiliações:
- Perm State Pharmaceutical Academy of the Health Protection Ministry of the Russian Federation
- Perm State National Research University
- Edição: Volume 53, Nº 11 (2017)
- Páginas: 1675-1677
- Seção: Article
- URL: https://bakhtiniada.ru/1070-4280/article/view/216927
- DOI: https://doi.org/10.1134/S1070428017110100
- ID: 216927
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Resumo
Three-component reaction of methyl benzoylpyruvate, aromatic aldehyde, and urea in methanol in the presence of sodium bisulfate stops at the stage of the formation of nondehydrated product with a methylated tertiary hydroxy group and results in methyl 6-aryl-5-benzoyl-4-methoxy-2-oxohexahydropyrimidine-4-carboxylates.
Sobre autores
V. Gein
Perm State Pharmaceutical Academy of the Health Protection Ministry of the Russian Federation
Autor responsável pela correspondência
Email: geinvl48@mail.ru
Rússia, ul. Polevaya 2, Perm, 614990
E. Gorgopina
Perm State Pharmaceutical Academy of the Health Protection Ministry of the Russian Federation
Email: geinvl48@mail.ru
Rússia, ul. Polevaya 2, Perm, 614990
T. Zamaraeva
Perm State Pharmaceutical Academy of the Health Protection Ministry of the Russian Federation
Email: geinvl48@mail.ru
Rússia, ul. Polevaya 2, Perm, 614990
M. Dmitriev
Perm State National Research University
Email: geinvl48@mail.ru
Rússia, Perm, 614990
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