Enviar artigo por via de e-mail Synthesis of N-aryl- and N,N-diethyl-9-methyl-11-sulfanylidene-8-oxa-10,12-diazatricyclo[7.3.1.02,7]trideca-2,4,6-triene-13-carboxamides
- Autores: Zamaraeva T.M.1, Gein V.L.1, Buzmakova N.A.1, Dmitriev M.V.2
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Afiliações:
- Perm State Pharmaceutical Academy
- Perm State National Research University
- Edição: Volume 52, Nº 7 (2016)
- Páginas: 1022-1025
- Seção: Article
- URL: https://bakhtiniada.ru/1070-4280/article/view/214716
- DOI: https://doi.org/10.1134/S1070428016070174
- ID: 214716
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Resumo
Three-component condensation of N-aryl- and N,N-diethyl-3-oxobutanamides with salicylaldehyde and thiourea in ethanol in the presence of sodium hydrogen sulfate afforded N-aryl- and N,N-diethyl-9-methyl-11-sulfanylidene-8-oxa-10,12-diazatricyclo[7.3.1.02,7]trideca-2,4,6-triene-13-carboxamides. Reaction of the same compounds in the absence of a catalyst under solvent-free conditions gave N-aryl-6-(2-hydroxyphenyl)-4-methyl-2-sulfanylidene-1,2,3,6-tetrahydropyrimidine-5-carboxamides.
Sobre autores
T. Zamaraeva
Perm State Pharmaceutical Academy
Autor responsável pela correspondência
Email: geinvl48@mail.ru
Rússia, ul. Polevaya 2, Perm, 614990
V. Gein
Perm State Pharmaceutical Academy
Email: geinvl48@mail.ru
Rússia, ul. Polevaya 2, Perm, 614990
N. Buzmakova
Perm State Pharmaceutical Academy
Email: geinvl48@mail.ru
Rússia, ul. Polevaya 2, Perm, 614990
M. Dmitriev
Perm State National Research University
Email: geinvl48@mail.ru
Rússia, ul. Bukireva 15, Perm, 614990
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