Synthesis of Aminomethoxy Derivatives of 1-(Butylsulfanyl)alkanes
- Авторлар: Jafarov I.A.1, Mammadbayli E.H.2, Jafarova N.A.3, Talybov G.M.2
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Мекемелер:
- Azerbaijan State Pedagogical University
- Institute of Petrochemical Processes
- Azerbaijan State University of Oil and Industry
- Шығарылым: Том 55, № 4 (2019)
- Беттер: 448-455
- Бөлім: Article
- URL: https://bakhtiniada.ru/1070-4280/article/view/220237
- DOI: https://doi.org/10.1134/S1070428019040055
- ID: 220237
Дәйексөз келтіру
Аннотация
Three-component Mannich-type condensation of equimolar amounts of 1-(butylsulfanyl)alkan-2-ols, formaldehyde, and secondary aliphatic and heterocyclic amines at 45–50°C (3–4 h) afforded 65–82% of previously unknown aminomethoxy derivatives which were characterized by elemental analyses and IR, 1H and 13C NMR, and mass spectra. Some of the synthesized compounds were tested for antimicrobial activity against gram negative, gram positive, and spore-bearing bacteria and yeast-like fungi; they showed a higher activity than commonly used antibacterial agents. Compounds containing cyclic amine fragments were more active than those obtained from aliphatic amines. The tested compounds were recommended for use as antimicrobial agents.
Авторлар туралы
I. Jafarov
Azerbaijan State Pedagogical University
Email: eldar_mamedbeyli@mail.ru
Әзірбайжан, Baku
E. Mammadbayli
Institute of Petrochemical Processes
Хат алмасуға жауапты Автор.
Email: eldar_mamedbeyli@mail.ru
Әзірбайжан, Baku
N. Jafarova
Azerbaijan State University of Oil and Industry
Email: eldar_mamedbeyli@mail.ru
Әзірбайжан, Baku
G. Talybov
Institute of Petrochemical Processes
Email: eldar_mamedbeyli@mail.ru
Әзірбайжан, Baku
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