Synthesis and biologic activity of aryloxyaminopropanoles based on substituted p-tolylalkylamines


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Аннотация

Reaction of 2,2-dimethyl-2-(p-tolyl)ethyl-, 1-p-tolylcyclopenthylmethyl- and 4-(p-tolyl)tetrahydro-2Н-pyran-4-ylmethylamines with phenoxymethyloxiranes substituted in the aromatic ring afforded new aryloxypropanolamines, some of which show moderate adrenoblocking activity.

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Авторлар туралы

A. Aghekyan

R&D Center of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of Armenia, Mndzhoyan Institute of Fine Organic Chemistry

Хат алмасуға жауапты Автор.
Email: aaghekyan@mail.ru
Армения, pr. Azatutyan 26, Yerevan, 0014

G. Mkryan

R&D Center of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of Armenia, Mndzhoyan Institute of Fine Organic Chemistry

Email: aaghekyan@mail.ru
Армения, pr. Azatutyan 26, Yerevan, 0014

A. Tsatinyan

R&D Center of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of Armenia, Mndzhoyan Institute of Fine Organic Chemistry

Email: aaghekyan@mail.ru
Армения, pr. Azatutyan 26, Yerevan, 0014

O. Noravyan

R&D Center of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of Armenia, Mndzhoyan Institute of Fine Organic Chemistry

Email: aaghekyan@mail.ru
Армения, pr. Azatutyan 26, Yerevan, 0014

G. Gasparyan

R&D Center of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of Armenia, Mndzhoyan Institute of Fine Organic Chemistry

Email: aaghekyan@mail.ru
Армения, pr. Azatutyan 26, Yerevan, 0014

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