Substituted 2-(2-Arylethenyl]pyrimidin-4(3H)-ones: Synthesis and Structure


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Abstract

5-Substituted 2,6-dimethylpyrimidin-4(3H)-ones were synthesized, and their structure was proved by X-ray analysis. Their reactions with aromatic aldehydes regioselectively afforded (Z)-2-(2-arylethenyl)- pyrimidin-4(3H)-ones whose structure was determined by one- and two-dimensional (NOESY) 1H NMR and X-ray analysis.

About the authors

A. A. Harutyunyan

Russian–Armenian (Slavonic) University; Mndzhoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry

Author for correspondence.
Email: harutyunyan.arthur@yahoo.com
Armenia, Hovsep Emin str. 123, Yerevan, 0051; Azatutyan ave. 26, Yerevan, 0014

G. A. Panosyan

Molecular Structure Research Center

Email: harutyunyan.arthur@yahoo.com
Armenia, Azatutyan ave. 26, Yerevan, 0014

R. A. Tamazyan

Molecular Structure Research Center

Email: harutyunyan.arthur@yahoo.com
Armenia, Azatutyan ave. 26, Yerevan, 0014

A. G. Aivazyan

Molecular Structure Research Center

Email: harutyunyan.arthur@yahoo.com
Armenia, Azatutyan ave. 26, Yerevan, 0014

G. T. Gukasyan

Russian–Armenian (Slavonic) University

Email: harutyunyan.arthur@yahoo.com
Armenia, Hovsep Emin str. 123, Yerevan, 0051

G. G. Danagulyan

Russian–Armenian (Slavonic) University; Mndzhoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry

Email: harutyunyan.arthur@yahoo.com
Armenia, Hovsep Emin str. 123, Yerevan, 0051; Azatutyan ave. 26, Yerevan, 0014

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