Email this article Reaction of trifluoroacetylchromenes with 6-aminouracils. Synthesis of pyrido[2,3-d]pyrimidines
- Authors: Popova Y.V.1, Osipov D.V.1, Osyanin V.A.1,2, Klimochkin Y.N.1
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Affiliations:
- Samara State Technical University
- Russian University of Peoples’ Friendship
- Issue: Vol 53, No 4 (2017)
- Pages: 599-603
- Section: Review
- URL: https://bakhtiniada.ru/1070-4280/article/view/216101
- DOI: https://doi.org/10.1134/S1070428017040169
- ID: 216101
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Abstract
The condensation of trifluoroacetyl-substituted 4H-chromenes and 1H-benzo[f]chromenes with 6-amino-1,3-dimethyluracil and 6-aminothiouracil afforded a number of pyrido[2,3-d]pyrimidine derivatives containing a 2-hydroxybenzyl or 2-hydroxynaphthalen-1-ylmethyl group in the 6-position as a result of cascade transformation initiated by Michael addition.
About the authors
Yu. V. Popova
Samara State Technical University
Email: VOsyanin@mail.ru
Russian Federation, ul. Molodogvardeiskaya 244, Samara, 443100
D. V. Osipov
Samara State Technical University
Email: VOsyanin@mail.ru
Russian Federation, ul. Molodogvardeiskaya 244, Samara, 443100
V. A. Osyanin
Samara State Technical University; Russian University of Peoples’ Friendship
Author for correspondence.
Email: VOsyanin@mail.ru
Russian Federation, ul. Molodogvardeiskaya 244, Samara, 443100; ul. Miklukho-Maklaya 6, Moscow, 117198
Yu. N. Klimochkin
Samara State Technical University
Email: VOsyanin@mail.ru
Russian Federation, ul. Molodogvardeiskaya 244, Samara, 443100
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