Reaction of trifluoroacetylchromenes with 6-aminouracils. Synthesis of pyrido[2,3- d ]pyrimidines

Yu. V. Popova; D. V. Osipov; V. A. Osyanin; Yu. N. Klimochkin

doi:10.1134/S1070428017040169

Reaction of trifluoroacetylchromenes with 6-aminouracils. Synthesis of pyrido[2,3-d]pyrimidines

作者: Popova Y.V.¹, Osipov D.V.¹, Osyanin V.A.¹^,2, Klimochkin Y.N.¹
隶属关系:
1. Samara State Technical University
2. Russian University of Peoples’ Friendship
期: 卷 53, 编号 4 (2017)
页面: 599-603
栏目: Review
URL: https://bakhtiniada.ru/1070-4280/article/view/216101
DOI: https://doi.org/10.1134/S1070428017040169
ID: 216101

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详细

The condensation of trifluoroacetyl-substituted 4H-chromenes and 1H-benzo[f]chromenes with 6-amino-1,3-dimethyluracil and 6-aminothiouracil afforded a number of pyrido[2,3-d]pyrimidine derivatives containing a 2-hydroxybenzyl or 2-hydroxynaphthalen-1-ylmethyl group in the 6-position as a result of cascade transformation initiated by Michael addition.