Email this article Synthesis of new derivatives of 5-(3,4-dihydro-2Н-pyrrol-5-yl)-pyrimidine
- Authors: Gasparyan S.P.1,2,3, Alexanyan M.V.1,3, Arutyunyan G.K.1,3, Kocharov S.L.1,3, Martirosyan A.H.1,3, Tamazyan R.A.4,3, Ayvazyan A.G.4,3, Panosyan H.A.4,3, Danagulyan G.G.2,3
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Affiliations:
- Mndzhoyan Institute of Fine Organic Chemistry
- Russian-Armenian (Slavonic) University
- R&D Center of Organic and Pharmaceutical Chemistry
- Center of Molecule Structure Research
- Issue: Vol 52, No 11 (2016)
- Pages: 1646-1653
- Section: Article
- URL: https://bakhtiniada.ru/1070-4280/article/view/215265
- DOI: https://doi.org/10.1134/S1070428016110166
- ID: 215265
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Abstract
By one-stage condensation of 6-(arylamino)pyrimidine-2,4(1Н,3Н)-diones with pyrrolidin-2-one new potential antiviral compounds were obtained, analogs of pyrrolinylpyrimidine containing structural fragments of known drugs AZT and HEPT used in treating HIV-infections.
About the authors
S. P. Gasparyan
Mndzhoyan Institute of Fine Organic Chemistry; Russian-Armenian (Slavonic) University; R&D Center of Organic and Pharmaceutical Chemistry
Author for correspondence.
Email: g_sahak@yahoo.com
Armenia, Yerevan; Yerevan; Yerevan
M. V. Alexanyan
Mndzhoyan Institute of Fine Organic Chemistry; R&D Center of Organic and Pharmaceutical Chemistry
Email: g_sahak@yahoo.com
Armenia, Yerevan; Yerevan
G. K. Arutyunyan
Mndzhoyan Institute of Fine Organic Chemistry; R&D Center of Organic and Pharmaceutical Chemistry
Email: g_sahak@yahoo.com
Armenia, Yerevan; Yerevan
S. L. Kocharov
Mndzhoyan Institute of Fine Organic Chemistry; R&D Center of Organic and Pharmaceutical Chemistry
Email: g_sahak@yahoo.com
Armenia, Yerevan; Yerevan
A. H. Martirosyan
Mndzhoyan Institute of Fine Organic Chemistry; R&D Center of Organic and Pharmaceutical Chemistry
Email: g_sahak@yahoo.com
Armenia, Yerevan; Yerevan
R. A. Tamazyan
Center of Molecule Structure Research; R&D Center of Organic and Pharmaceutical Chemistry
Email: g_sahak@yahoo.com
Armenia, pr. Azatutyan 26, Yerevan, 0014; Yerevan
A. G. Ayvazyan
Center of Molecule Structure Research; R&D Center of Organic and Pharmaceutical Chemistry
Email: g_sahak@yahoo.com
Armenia, pr. Azatutyan 26, Yerevan, 0014; Yerevan
H. A. Panosyan
Center of Molecule Structure Research; R&D Center of Organic and Pharmaceutical Chemistry
Email: g_sahak@yahoo.com
Armenia, pr. Azatutyan 26, Yerevan, 0014; Yerevan
G. G. Danagulyan
Russian-Armenian (Slavonic) University; R&D Center of Organic and Pharmaceutical Chemistry
Email: g_sahak@yahoo.com
Armenia, Yerevan; Yerevan
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