Synthesis of New Derivatives of 2-Imino-2,5-dihydrofuran-3-carboxamides, Containing Aromatic Substituents

Abstract

Novel derivatives of 2-imino-2,5-dihydrofuran-3-carboxamides containing aromatic substituents in positions 2 and 4 of the iminodihydrofuran ring were synthesized by the reaction of 2-imino-2,5-dihydrofuran-3-carboxamides with benzylamine in glacial acetic acid. The structure of the synthesized compounds was proved by spectral methods (¹H and ¹³C NMR) and by an independent synthesis by the reaction of the previously synthesized 2-imino-5,5-dimethyl-4-(2-phenylvinyl)-2,5-dihydrofuran-3-carboxamide with benzylamine in glacial acetic acid.