Synthesis and Biological Activity of Substituted Spiro[chromene-4,3′-indoles] and Spiro[indole-3,4′-quinolines]

S. A. Pogosyan; M. V. Pogosyan; L. R. Aleksanyan; A. S. Safaryan; A. G. Arakelyan

doi:10.1134/S1070428018120254

Synthesis and Biological Activity of Substituted Spiro[chromene-4,3′-indoles] and Spiro[indole-3,4′-quinolines]

Authors: Pogosyan S.A.¹, Pogosyan M.V.¹, Aleksanyan L.R.¹, Safaryan A.S.¹, Arakelyan A.G.¹
Affiliations:
1. Mndzhoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry
Issue: Vol 54, No 12 (2018)
Pages: 1860-1863
Section: Short Communications
URL: https://bakhtiniada.ru/1070-4280/article/view/219644
DOI: https://doi.org/10.1134/S1070428018120254
ID: 219644

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Abstract

New substituted spiro[chromene-4,3′-indoles] and spiro[indole-3,4′-quinolines] have been synthesized in 35–65% yields by one-pot regioselective three-component condensation of N-substituted isatins with two active methylene compounds.