Synthesis of meta-Carboranyl-(S)-homocysteine Sulfoxide


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Resumo

New (S)-homocysteine derivatives containing a meta-carborane fragment were synthesized. m-Carboranyl-(S)-homocysteine sulfoxide was obtained as a mixture of diastereoisomers. The reduction of the side-chain carboxy group of N-tert-butoxycarbonyl-(S)-aspartic acid α-tert-butyl ester with sodium tetrahydridoborate was not accompanied by racemization.

Sobre autores

D. Gruzdev

Postovskii Institute of Organic Synthesis, Ural Branch

Autor responsável pela correspondência
Email: gruzdev-da@ios.uran.ru
Rússia, ul. S. Kovalevskoi/Akademicheskaya 22/20, Yekaterinburg, 620990

V. Ustinova

Postovskii Institute of Organic Synthesis, Ural Branch

Email: gruzdev-da@ios.uran.ru
Rússia, ul. S. Kovalevskoi/Akademicheskaya 22/20, Yekaterinburg, 620990

G. Levit

Postovskii Institute of Organic Synthesis, Ural Branch

Email: gruzdev-da@ios.uran.ru
Rússia, ul. S. Kovalevskoi/Akademicheskaya 22/20, Yekaterinburg, 620990

V. Ol’shevskaya

Nesmeyanov Institute of Organoelement Compounds

Email: gruzdev-da@ios.uran.ru
Rússia, ul. Vavilova 28, Moscow, 119991

V. Krasnov

Postovskii Institute of Organic Synthesis, Ural Branch

Email: gruzdev-da@ios.uran.ru
Rússia, ul. S. Kovalevskoi/Akademicheskaya 22/20, Yekaterinburg, 620990

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