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Synthesis of 3-Benzylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione


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Abstract

3-Benzylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione [cyclo(Pro-Phe)] was synthesized by cyclization of prolylphenylalanine and phenylalanylproline methyl esters which were prepared from the corresponding Boc-protected amino acids.

About the authors

V. A. Gaidukevich

Institute of Physical Organic Chemistry

Email: knizh@ifoch.bas-net.by
Belarus, ul. Surganova 13, Minsk, 220072

I. V. Rudenkova

Institute of Physiology

Email: knizh@ifoch.bas-net.by
Belarus, ul. Akademicheskaya 28, Minsk, 220072

L. A. Popova

Institute of Physical Organic Chemistry

Email: knizh@ifoch.bas-net.by
Belarus, ul. Surganova 13, Minsk, 220072

L. N. Nikolaevich

Institute of Physiology

Email: knizh@ifoch.bas-net.by
Belarus, ul. Akademicheskaya 28, Minsk, 220072

V. A. Knizhnikov

Institute of Physical Organic Chemistry

Author for correspondence.
Email: knizh@ifoch.bas-net.by
Belarus, ul. Surganova 13, Minsk, 220072

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