Regioselective synthesis of benzo[g]- and benzo[f]quinolines by reaction of chalcones with naphthalen-2-amine

Аннотация

Reactions of 4- and 4′-substituted chalcones with naphthalen-2-amine afforded isomeric benzo[g]- and benzo[f]quinoline derivatives. Depending on the substituent in the initial chalcone, the cyclization follows two pathways through different intermediates. The product structure was confirmed by IR, ¹H and ¹³C NMR, and mass spectra and X-ray analysis.