Enviar artigo por via de e-mail Cyclic Amidoalkylation of Hydrophosphorylic Compounds. Synthesis of Proline Analogs
- Autores: Vinyukov A.V.1, Dmitriev M.E.1, Yarkevich A.N.1, Ragulin V.V.1
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Afiliações:
- Institute of Physiologically Active Substances
- Edição: Volume 87, Nº 12 (2017)
- Páginas: 2898-2901
- Seção: Letters to the Editor
- URL: https://bakhtiniada.ru/1070-3632/article/view/221731
- DOI: https://doi.org/10.1134/S107036321712026X
- ID: 221731
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Resumo
A method for the synthesis of N-Cbz-protected phosphorylic analogs of proline by cyclic amidoalkylation of various hydrophosphorylic compounds was developed. Combination of amide and carbonyl fragments in the 4-N-Cbz-aminobutyraldehyde molecule allows to realize the three-center two-component amide version of the Kabachnik–Fields reaction.
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Sobre autores
A. Vinyukov
Institute of Physiologically Active Substances
Email: rvalery@dio.ru
Rússia, Severnyi proezd 1, Chernogolovka, Moscow oblast, 142432
M. Dmitriev
Institute of Physiologically Active Substances
Email: rvalery@dio.ru
Rússia, Severnyi proezd 1, Chernogolovka, Moscow oblast, 142432
A. Yarkevich
Institute of Physiologically Active Substances
Email: rvalery@dio.ru
Rússia, Severnyi proezd 1, Chernogolovka, Moscow oblast, 142432
V. Ragulin
Institute of Physiologically Active Substances
Autor responsável pela correspondência
Email: rvalery@dio.ru
Rússia, Severnyi proezd 1, Chernogolovka, Moscow oblast, 142432
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