Synthesis of 2N-Alkyl-substituted 5-Amino-3-imino-1,2,4-thiadiazolines

Abstract

Conditions for an efficient and a readily reproducible synthesis of a series of 2N-Alkyl-substituted 5-amino-3-imino-1,2,4-thiadiazolines by the direct alkylation of 3,5-diamino-1,2,4-thiadiazole with alkyl bromides in fairly high yields (up to 76%).