Отправить статью по E-mail Synthesis and membrane protective activity of 4-alkoxymethyl-2,6-diisobornylphenols
- Авторы: Buravlev E.V.1, Chukicheva I.Y.1, Shevchenko O.G.2, Suponitsky K.Y.3, Kutchin A.V.1
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Учреждения:
- Institute of Chemistry of Komi Scientific Center, Ural Branch of the Russian Academy of Sciences
- Institute of Biology of Komi Scientific Center, Ural Branch of the Russian Academy of Sciences
- A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
- Выпуск: Том 65, № 5 (2016)
- Страницы: 1232-1237
- Раздел: Full Articles
- URL: https://bakhtiniada.ru/1066-5285/article/view/238071
- DOI: https://doi.org/10.1007/s11172-016-1440-x
- ID: 238071
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Аннотация
Bromination of 2,6-diisobornyl-4-methylphenol gave the corresponding 4-bromomethyl derivative, whose reaction with alcohols resulted in 4-alkoxymethyl-2,6-diisobornylphenols. Their toxicity, membrane protective and antioxidant activity were tested using red blood cells of laboratory mice. The synthesized compounds do not exhibit cytotoxicity at the concentrations of 10 and 100 μmol L–1 and are characterized by high membrane protective and antioxidant activity in the concentrations of 1 and 10 μmol L–1.
Об авторах
E. Buravlev
Institute of Chemistry of Komi Scientific Center, Ural Branch of the Russian Academy of Sciences
Автор, ответственный за переписку.
Email: eugeneburavlev@gmail.com
Россия, 48 ul. Pervomaiskaya, Syktyvkar, 167982
I. Chukicheva
Institute of Chemistry of Komi Scientific Center, Ural Branch of the Russian Academy of Sciences
Email: eugeneburavlev@gmail.com
Россия, 48 ul. Pervomaiskaya, Syktyvkar, 167982
O. Shevchenko
Institute of Biology of Komi Scientific Center, Ural Branch of the Russian Academy of Sciences
Email: eugeneburavlev@gmail.com
Россия, 28 ul. Kommunisticheskaya, Syktyvkar, 167982
K. Suponitsky
A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
Email: eugeneburavlev@gmail.com
Россия, 28 ul. Vavilova, Moscow, 119991
A. Kutchin
Institute of Chemistry of Komi Scientific Center, Ural Branch of the Russian Academy of Sciences
Email: eugeneburavlev@gmail.com
Россия, 48 ul. Pervomaiskaya, Syktyvkar, 167982
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