Conjugation of indole derivatives by copper-catalyzed alkyne-azide cycloaddition


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An efficient synthetic procedure to combine biologically active indole derivatives by the triazole-containing spacer in a molecule has been proposed. The procedure was based on a copper-catalyzed alkyne-azide cycloaddition of azide-containing carbazoles and N-propargyl-containing carbazoles, tetrahydrocarbazoles, and tetrahydro-γ-carbolines.

Sobre autores

V. Sokolov

Institute of Physiologically Active Compounds, Russian Academy of Sciences

Autor responsável pela correspondência
Email: alaks@ipac.ac.ru
Rússia, 1 Severnyi proezd, >Moscow Region, Chernogolovka, 142432

А. Aksinenko

Institute of Physiologically Active Compounds, Russian Academy of Sciences

Email: alaks@ipac.ac.ru
Rússia, 1 Severnyi proezd, >Moscow Region, Chernogolovka, 142432

Т. Epishina

Institute of Physiologically Active Compounds, Russian Academy of Sciences

Email: alaks@ipac.ac.ru
Rússia, 1 Severnyi proezd, >Moscow Region, Chernogolovka, 142432

Т. Goreva

Institute of Physiologically Active Compounds, Russian Academy of Sciences

Email: alaks@ipac.ac.ru
Rússia, 1 Severnyi proezd, >Moscow Region, Chernogolovka, 142432

S. Bachurin

Institute of Physiologically Active Compounds, Russian Academy of Sciences

Email: alaks@ipac.ac.ru
Rússia, 1 Severnyi proezd, >Moscow Region, Chernogolovka, 142432

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