Отправить статью по E-mail Three-component green synthesis of 6-ethoxycarbonyl-5-methyl-7-(thien-2-yl)-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine, a promising antituberculosis drug
- Авторы: Titova Y.A.1, Fedorova O.V.1, Rusinov G.L.1,2, Charushin V.N.1,2
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Учреждения:
- I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
- Ural Federal University named after the first President of Russia B. N. Yeltsin
- Выпуск: Том 68, № 12 (2019)
- Страницы: 2271-2274
- Раздел: Full Articles
- URL: https://bakhtiniada.ru/1066-5285/article/view/243558
- DOI: https://doi.org/10.1007/s11172-019-2698-6
- ID: 243558
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Аннотация
A new simple, technological, and environmentally friendly method for the catalyst-free synthesis in water of a promising antituberculosis drug, 6-ethoxycarbonyl-5-methyl-7-(thien-2-yl)-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine, was developed. The amount of the solvent in the reaction mixture has a decisive effect on the yield and purity of the target product.
Об авторах
Yu. Titova
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Автор, ответственный за переписку.
Email: titova@ios.uran.ru
Россия, 22 ul. S. Kovalevskoi, Yekaterinburg, 620990
O. Fedorova
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: titova@ios.uran.ru
Россия, 22 ul. S. Kovalevskoi, Yekaterinburg, 620990
G. Rusinov
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural Federal University named after the first President of Russia B. N. Yeltsin
Email: titova@ios.uran.ru
Россия, 22 ul. S. Kovalevskoi, Yekaterinburg, 620990; 19 ul. Mira, Yekaterinburg, 620002
V. Charushin
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural Federal University named after the first President of Russia B. N. Yeltsin
Email: titova@ios.uran.ru
Россия, 22 ul. S. Kovalevskoi, Yekaterinburg, 620990; 19 ul. Mira, Yekaterinburg, 620002
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